CAS 20874-52-6

Saikosaponina D

Descripción:

Saikosaponina D es un saponina triterpenoide derivada principalmente de las raíces de la planta Bupleurum falcatum, conocida comúnmente por su uso en la medicina tradicional. Se caracteriza por su estructura compleja, que incluye un esqueleto similar a un esteroide con varios moieties de azúcar adjuntos, lo que contribuye a su actividad biológica. Saikosaponina D exhibe una variedad de propiedades farmacológicas, incluyendo efectos antiinflamatorios, hepatoprotectores e inmunomoduladores. Se piensa que su mecanismo de acción implica la modulación de varias vías de señalización, incluidas las relacionadas con la apoptosis y la proliferación celular. Además, se ha estudiado Saikosaponina D por sus posibles propiedades anticancerígenas, mostrando promesas en la inhibición del crecimiento tumoral en varias líneas celulares de cáncer. La sustancia es típicamente soluble en agua y solventes orgánicos, lo que la hace adecuada para varios procesos de extracción y formulación. Al igual que muchos compuestos naturales, se están realizando más investigaciones para esclarecer completamente su potencial terapéutico y mecanismos de acción, así como para explorar su seguridad y eficacia en aplicaciones clínicas.

Fórmula: C₄₂H₆₈O₁₃

InChI: InChI=1S/C42H68O13/c1-21-28(46)33(55-34-31(49)30(48)29(47)22(18-43)53-34)32(50)35(52-21)54-27-10-11-37(4)23(38(27,5)19-44)8-12-39(6)24(37)9-13-42-25-16-36(2,3)14-15-41(25,20-51-42)26(45)17-40(39,42)7/h9,13,21-35,43-50H,8,10-12,14-20H2,1-7H3/t21-,22-,23-,24-,25?,26-,27+,28+,29-,30+,31-,32-,33+,34+,35+,37+,38+,39-,40+,41-,42+/m1/s1

Clave InChI: InChIKey=KYWSCMDFVARMPN-VFDNYBEVSA-N

SMILES: C[C@]12[C@@]3(C4([C@@](CO3)([C@H](O)C1)CCC(C)(C)C4)[H])C=C[C@]5([C@@]2(C)CC[C@@]6([C@]5(C)CC[C@H](O[C@H]7[C@H](O)[C@@H](O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@@H](O)[C@@H](C)O7)[C@]6(CO)C)[H])[H]

Sinónimos:

• (3beta,13alpha,16alpha,17alpha)-16,23-dihydroxy-13,28-epoxyolean-11-en-3-yl 6-deoxy-3-O-beta-D-glucopyranosyl-beta-D-galactopyranoside
• (3beta,16alpha)-16,23-Dihydroxy-13,28-epoxyolean-11-en-3-yl 6-deoxy-3-O-beta-D-glucopyranosyl-beta-D-galactopyranoside
• (3β,4α,16α)-13,28-Epoxy-16,23-dihydroxyolean-11-en-3-yl 6-deoxy-3-O-β-<span class="text-smallcaps">D</smallcap>-glucopyranosyl-β-<smallcap>D</span>-galactopyranoside
• beta-D-galactopyranoside, (3beta,16alpha)-13,28-epoxy-16,23-dihydroxyolean-11-en-3-yl 6-deoxy-3-O-beta-D-glucopyranosyl-
• sailkosaponin D
• β-<span class="text-smallcaps">D</smallcap>-Galactopyranoside, (3β,4α,16α)-13,28-epoxy-16,23-dihydroxyolean-11-en-3-yl 6-deoxy-3-O-β-<smallcap>D</span>-glucopyranosyl-
• Saikosaponin D
• (3β,4α,16α)-13,28-Epoxy-16,23-dihydroxyolean-11-en-3-yl 6-deoxy-3-O-β-D-glucopyranosyl-β-D-galactopyranoside
• β-D-Galactopyranoside, (3β,4α,16α)-13,28-epoxy-16,23-dihydroxyolean-11-en-3-yl 6-deoxy-3-O-β-D-glucopyranosyl-

β-D-Galactopyranoside, (3β,4α,16α)-13,28-epoxy-16,23-dihydroxyolean-11-en-3-yl 6-deoxy-3-O-β-D-glucopyranosyl-

CAS: 20874-52-6

Fórmula: C₄₂H₆₈O₁₃

Pureza: %

Forma y color: Solid

Peso molecular: 780.9815

Ref: IN-DA002JVD

Saikosaponin D

CAS: 20874-52-6

Saikosaponin D

Fórmula: C₄₂H₆₈O₁₃

Pureza: ≥98%

Peso molecular: 780.993

Ref: 54-BUP10684

Saikosaponin D

CAS: 20874-52-6

Fórmula: C₄₂H₆₈O₁₃

Peso molecular: 780.98

Ref: 7W-GC1918

Saikosaponin D

CAS: 20874-52-6

Fórmula: C₄₂H₆₈O₁₃

Pureza: >98.0%(HPLC)

Forma y color: White to Almost white powder to crystal

Peso molecular: 780.99

Ref: 3B-A3405

Saikosaponin D

CAS: 20874-52-6

SaikosaponinD (SSd) is a major triterpenoid saponin derivative from Radix bupleuri, which has been long used in Chinese traditional medicine for treatment of various inflammation-related diseases; it shows potent anti-inflammatory activity through inhibitory effects on NF-κB activation and thereby on iNOS, COX-2 and pro-inflammatory cytokines.

Fórmula: C₄₂H₆₈O₁₃

Pureza: 95%~99%

Forma y color: Powder

Peso molecular: 780.993

Ref: BP-BP1242

Saikosaponin D

CAS: 20874-52-6

Saikosaponin D is a novel SERCA inhibitor by inhibiting NF-κB and STAT3 signaling to protect against acetaminophen-induced hepatotoxicity.

Fórmula: C₄₂H₆₈O₁₃

Pureza: 98.34% - 99.73%

Forma y color: White Solid

Peso molecular: 780.98

Ref: TM-T3913

Saikosaponin D

CAS: 20874-52-6

(2S,3R,4S,5S,6R)-2-(((2R,3R,4S,5S,6R)-3,5-Dihydroxy-2-(((3S,4R,4aR,6aR,6bS,8R,8aS,12aR,12bS,14aR,14bS)-8-hydroxy-4-(hydroxymethyl)-4,6a,6b,11,11,14b-hexamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,9,10,11,12,12a,14a,14b-octadecahydro-12b,8a-(epoxymethano)picen-3-yl)oxy)-6-methyltetrahydro-2H-pyran-4-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

Fórmula: C₄₂H₆₈O₁₃

Pureza: 98+%

Peso molecular: 780.98

Ref: IN-DG32606

Saikosaponin D

CAS: 20874-52-6

Natural glycoside

Fórmula: C₄₂H₆₈O₁₃

Pureza: ≥ 90.0 % (HPLC)

Forma y color: Powder

Peso molecular: 781

Ref: 5G-89527

Saikosaponin D

Producto controlado

CAS: 20874-52-6

Applications Saikosaponin D is an inhibitor of proliferation of human prostate cancer cells through arresting the cell cycle.
References Yao, M. et al.: Mol. Med. Rep., 10, 365 (2014); Li, Z. et al.: Prog. Neuro-Psychopharm. Biol. Psych., 53, 80 (2014);

Fórmula: C₄₂H₆₈O₁₃

Forma y color: Neat

Peso molecular: 780.98

Ref: TR-S083915

Saikosaponin D

CAS: 20874-52-6

Saikosaponin D is a bioactive compound, specifically a triterpenoid saponin, which is derived from the roots of Bupleurum species, plants commonly used in traditional Chinese medicine. Its mode of action involves modulating key pathways in inflammation and apoptosis. This compound targets cellular mechanisms by interacting with inflammatory mediators and apoptotic proteins, thereby influencing immune responses and cellular survival.

Fórmula: C₄₂H₆₈O₁₃

Pureza: Min. 98 Area-%

Forma y color: White Powder

Peso molecular: 780.98 g/mol

Ref: 3D-OS09508

Saikosaponin d

CAS: 20874-52-6

Ref: BE-RMT10750

Saikosaponin d

CAS: 20874-52-6

Ref: BE-促RMT10750