CAS 2089065-77-8

Fórmula: C28H32Br2N8O6S2

InChI: InChI=1S/C28H32Br2N8O6S2/c1-3-13-35-45(39,40)37-25-23(19-5-9-21(29)10-6-19)27(33-17-31-25)43-15-16-44-28-24(20-7-11-22(30)12-8-20)26(32-18-34-28)38-46(41,42)36-14-4-2/h5-12,17-18,35-36H,3-4,13-16H2,1-2H3,(H,31,33,37)(H,32,34,38)

Clave InChI: AHHRKAUBXBVVDS-UHFFFAOYSA-N

SMILES: CCCNS(=O)(=O)NC1=C(C(=NC=N1)OCCOC2=NC=NC(=C2C3=CC=C(C=C3)Br)NS(=O)(=O)NCCC)C4=CC=C(C=C4)Br

Macitentan Sulfamide Dimer

CAS: 2089065-77-8

Compounds containing a pyrimidine ring, whether or not hydrogenated, or piperazine ring in the structure, nesoi

Fórmula: C₂₈H₃₂Br₂N₈O₆S₂

Forma y color: Off-White Solid

Peso molecular: 798.0253

Ref: 45-1A05660

Macitentan Impurity 4

CAS: 2089065-77-8

Fórmula: C₂₈H₃₂Br₂N₈O₆S₂

Forma y color: White To Off-White Solid

Peso molecular: 800.54

Ref: 4Z-M-128008

Macitentan Sulfamide Dimer

Producto controlado

CAS: 2089065-77-8

Applications O-Desbromo-pyrimidinyl O-[6-N-(N'-propyl)sulfamido-5-(4-bromophenyl)pyrimidin-4-yl] Macitentan is an impurity of Macitentan (M105005); a dual orally active and potent endothelin receptor antagonist used for pulmonary arterial hypertension.
References Emoto, N. Ensho to Men'eki, 20, 487 (2012); Bruderer, S., et al.: Xenobiotica, 42, 901 (2012); Bolli, M.H., et al.: J. Med. Chem., 55, 7849 (2012)

Fórmula: C₂₈H₃₂Br₂N₈O₆S₂

Forma y color: Neat

Peso molecular: 800.54

Ref: TR-D282005

Macitentan Dimer Impurity

CAS: 2089065-77-8

Fórmula: C₂₈H₃₂Br₂N₈O₆S₂

Peso molecular: 800.54

Ref: ST-EA-CP-M5014