CAS 211914-51-1

Dabigatrán

Descripción:

Dabigatrán es un medicamento anticoagulante oral que se utiliza principalmente para la prevención y tratamiento de trastornos tromboembólicos, como la fibrilación auricular y la trombosis venosa profunda. Funciona como un inhibidor directo de la trombina, lo que significa que inhibe directamente la actividad de la trombina, una enzima crucial para la formación de coágulos sanguíneos. La fórmula química de Dabigatrán es C19H21N7O5S, y presenta una estructura única que incluye un grupo ácido carboxílico, un grupo amino y un moiety sulfonamida. Dabigatrán se caracteriza por su alta biodisponibilidad y rápido inicio de acción, lo que lo hace efectivo para el manejo de trastornos de coagulación. Se administra típicamente como un profármaco, Dabigatrán etexilato, que se convierte en su forma activa en el cuerpo. La sustancia es conocida por su farmacocinética predecible, lo que permite una dosificación fija sin necesidad de monitoreo rutinario de los niveles de anticoagulación, a diferencia de los anticoagulantes tradicionales como la warfarina. Sin embargo, es esencial considerar los posibles efectos secundarios, incluidos los riesgos de sangrado, y usarlo bajo supervisión médica.

Fórmula: C₂₅H₂₅N₇O₃

InChI: InChI=1/C25H25N7O3/c1-31-20-10-7-17(25(35)32(13-11-23(33)34)21-4-2-3-12-28-21)14-19(20)30-22(31)15-29-18-8-5-16(6-9-18)24(26)27/h2-10,12,14,29H,11,13,15H2,1H3,(H3,26,27)(H,33,34)

Clave InChI: InChIKey=YBSJFWOBGCMAKL-UHFFFAOYSA-N

SMILES: CN1C=2C(=CC(C(N(CCC(O)=O)C3=CC=CC=N3)=O)=CC2)N=C1CNC4=CC=C(C(=N)N)C=C4

Sinónimos:

• 3-[[2-[[(4-Carbamimidoylphenyl)Amino]Methyl]-1-Methyl-Benzoimidazole-5-Carbonyl]-Pyridin-2-Yl-Amino]Propanoic Acid
• Bibr 953
• Bibr 953Zw
• Dabigatran
• N-(2-(4-(N-(Hexyloxycarbonyl)Amidino)Phenylaminomethyl)-1-Methyl-1H-Benzimidazol-5-Ylcarbonyl)-N-(2-Pyridyl)-Beta-Alanine Ethyl Ester
• N-[[2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-β-alanine
• beta-alanine, N-[[2-[[[4-(aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-
• β-Alanine, N-[[2-[[[4-(aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-
• N-[(2-{[(4-carbamimidoylphenyl)amino]methyl}-1-methyl-1H-ben...
• N-[[2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-beta-alanine
• Dabiga group
• BIBR953;BIBR 953;BIBR-953
• Dabigatran etexilate impurity1513
• 3-[[2-[[(4-carbaMiMidoylphenyl)aMino]Methyl]-1-Met
• BIBR 953 (Dabigatran, Pradaxa)
• Dabigatran(BIB-953
• Dabigatran Q: What is the CAS Number of
• BIB-953
• 3-(2-((4-carbamimidoylphenylamino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoic acid
• BIBR 953(Dabigatran)
• Dabigatran Etexilate Mesilate
• Dabigatran etexilate-1
• Dabigatran base
• 3-[[2-[[(4-carbaMiMidoylphenyl)aMino]Methyl]-1-Methyl-benzoiMidazole-5-carbonyl]-pyridin-2-yl-aMino]
• 3-[[2-[(4-carbamimidoylanilino)methyl]-1-methylbenzimidazole-5-carbonyl]-pyridin-2-ylamino]propanoic
• Dabigatran3-(2-((4-carbamimidoylphenylamino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoic acid
• Dabigatran Ester Impurity B
• Dabigatran API
• BIBR 953;BIBR 953ZW;BIBR953;BIB-953
• Dabigatran Impurity U
• 3-[[2-[(4-carbamimidoylanilino)methyl]-1-methylbenzimidazole-5-carbonyl]-pyridin-2-ylamino]propanoic acid
• 3-[[2-[(4-carbamimidoylanilino)methyl]-1-methylbenzimidazole-5-carbonyl]-pyridin-2-ylamino]propanoic acid Dabigatran (BIBR 953)
• Dabigatran (Acid)
• ethyl 3-(2-(((4-(N'-((hexan-2-yloxy)carbonyl)carbamimidoyl)phenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate
• N-[[2-[[[4-(AMinoiMinoMethyl)phenyl]aMino]Methyl]-1-Methyl-1H-benzo[d]iMidazol-5-yl]carbonyl]-N-pyridin-2-yl-beta-alanine
• DabigatranQ: What is
• Dabigatran (BIBR 953)
• Dabigatran etexilate impurity189
• Dabigatran Impurity b
• N- (2-{ (4-carbaMiMidoylphenyl)aMino Methyl}-1-Met
• Dabigatran Q: What are the applications of
• Dabigatran Q: What is the storage condition of
• Dabigatran USP/EP/BP
• CS-1864
• N-[(2-{[(4-carbaMiMidoylphenyl)aMino]Methyl}-1-Methyl-1HbenziMidazol-

3-[1-(2-{[(4-carbamimidoylphenyl)amino]methyl}-1-methyl-1H-1,3-benzodiazol-5-yl)-N-(pyridin-2-yl)formamido]propanoic acid

CAS: 211914-51-1

Fórmula: C₂₅H₂₅N₇O₃

Pureza: 98%

Forma y color: Solid

Peso molecular: 471.5111

Ref: IN-DA00I41W

3-(2-(((4-Carbamimidoylphenyl)Amino)Methyl)-1-Methyl-N-(Pyridin-2-Yl)-1H-Benzo[D]Imidazole-5-Carboxamido)Propanoic Acid

CAS: 211914-51-1

3-(2-(((4-Carbamimidoylphenyl)Amino)Methyl)-1-Methyl-N-(Pyridin-2-Yl)-1H-Benzo[D]Imidazole-5-Carboxamido)Propanoic Acid

Pureza: 98%

Peso molecular: 471.51g/mol

Ref: 54-OR1010625

Dabigatran

CAS: 211914-51-1

Fórmula: C₂₅H₂₅N₇O₃

Forma y color: White To Off-White Solid

Peso molecular: 471.52

Ref: 4Z-D-591

Dabigatran-13C-d3

CAS: 211914-51-1

Fórmula: C₂₄₁₃CH₂₂D₃N₇O₃

Forma y color: White To Off-White Solid

Peso molecular: 475.53

Ref: 4Z-D-59109

Dabigatran

CAS: 211914-51-1

Dabigatran

Pureza: ≥95%

Peso molecular: 471.51g/mol

Ref: 54-BUP05533

N-Nitroso Dabigatran Etexilate-13C-d3

CAS: 211914-51-1

Fórmula: C₃₃₁₃CH₃₇D₃N₈O₆

Forma y color: White To Off-White Solid

Peso molecular: 660.75

Ref: 4Z-D-59138

Dabigatran

CAS: 211914-51-1

Fórmula: C₂₅H₂₅N₇O₃

Pureza: >95.0%(HPLC)

Forma y color: White to Light yellow powder to crystal

Peso molecular: 471.52

Ref: 3B-D5902

Dabigatran

CAS: 211914-51-1

Forma y color: Neat

Ref: 86-MM3522.02

Dabigatran

CAS: 211914-51-1

Dabigatran (BIBR 953ZW), a thrombin inhibitor, prevents thrombus formation, reducing stroke and embolism risk in nonvalvular atrial fibrillation patients.

Fórmula: C₂₅H₂₅N₇O₃

Pureza: 97.44% - 98.7%

Forma y color: Tan Solid

Peso molecular: 471.51

Ref: TM-T6295

Dabigatran

CAS: 211914-51-1

Applications Nonpeptide, direct thrombin inhibitor. Antithrombotic.
References Hauel, N., et al.: J. Med. Chem., 45, 1757 (2002), Mungall, D., et al.: Curr. Opin. Invest. Drugs, 3, 095 (2002), Stangier, J., et al.: J. Clin. Pharmacol., 45, 555 (2005),

Fórmula: C₂₅H₂₅N₇O₃

Forma y color: Neat

Peso molecular: 471.51

Ref: TR-D100090

Dabigatran-d7 (>90%)

Producto controlado

CAS: 211914-51-1

Applications Dabigatran-d7, is the labeled analogue of Dabigatran (D100090), Nonpeptide, direct thrombin inhibitor. Antithrombotic.
References Hauel, N., et al.: J. Med. Chem., 45, 1757 (2002), Mungall, D., et al.: Curr. Opin. Invest. Drugs, 3, 095 (2002), Stangier, J., et al.: J. Clin. Pharmacol., 45, 555 (2005),

Fórmula: C₂₅H₁₈D₇N₇O₃

Forma y color: Neat

Peso molecular: 478.55

Ref: TR-D100093

Dabigatran

CAS: 211914-51-1

Fórmula: C₂₅H₂₅N₇O₃

Peso molecular: 471.51

Ref: ST-EA-CP-D5003

Dabigatran

CAS: 211914-51-1

Dabigatran is an oral prodrug that is converted to dabigatran etexilate by esterases in the blood. Dabigatran etexilate is an anticoagulant that inhibits thrombin formation and also prevents the conversion of fibrinogen to fibrin. The drug is used for the prevention of stroke or embolism in people with atrial fibrillation, as well as treatment and prevention of deep venous thrombosis and pulmonary embolism. Dabigatran etexilate has a long half-life of 15-20 hours, meaning that it can be administered once daily. There are two analytical methods for measuring dabigatran concentrations in plasma: one based on the activity of the drug's main metabolite (dabigatran etexilate) and another based on both dabigatran and its active metabolite (dabigatran etexil

Fórmula: C₂₅H₂₅N₇O₃

Pureza: Min. 95%

Forma y color: White Powder

Peso molecular: 471.51 g/mol

Ref: 3D-FD32710

DABIGATRAN

CAS: 211914-51-1

Pureza: 98%

Peso molecular: 471.5209961

Ref: 10-F799805