CAS 211914-51-1
:Dabigatrán
Descripción:
Dabigatrán es un medicamento anticoagulante oral que se utiliza principalmente para la prevención y tratamiento de trastornos tromboembólicos, como la fibrilación auricular y la trombosis venosa profunda. Funciona como un inhibidor directo de la trombina, lo que significa que inhibe directamente la actividad de la trombina, una enzima crucial para la formación de coágulos sanguíneos. La fórmula química de Dabigatrán es C19H21N7O5S, y presenta una estructura única que incluye un grupo ácido carboxílico, un grupo amino y un moiety sulfonamida. Dabigatrán se caracteriza por su alta biodisponibilidad y rápido inicio de acción, lo que lo hace efectivo para el manejo de trastornos de coagulación. Se administra típicamente como un profármaco, Dabigatrán etexilato, que se convierte en su forma activa en el cuerpo. La sustancia es conocida por su farmacocinética predecible, lo que permite una dosificación fija sin necesidad de monitoreo rutinario de los niveles de anticoagulación, a diferencia de los anticoagulantes tradicionales como la warfarina. Sin embargo, es esencial considerar los posibles efectos secundarios, incluidos los riesgos de sangrado, y usarlo bajo supervisión médica.
Fórmula:C25H25N7O3
InChI:InChI=1/C25H25N7O3/c1-31-20-10-7-17(25(35)32(13-11-23(33)34)21-4-2-3-12-28-21)14-19(20)30-22(31)15-29-18-8-5-16(6-9-18)24(26)27/h2-10,12,14,29H,11,13,15H2,1H3,(H3,26,27)(H,33,34)
Clave InChI:InChIKey=YBSJFWOBGCMAKL-UHFFFAOYSA-N
SMILES:CN1C=2C(=CC(C(N(CCC(O)=O)C3=CC=CC=N3)=O)=CC2)N=C1CNC4=CC=C(C(=N)N)C=C4
Sinónimos:- 3-[[2-[[(4-Carbamimidoylphenyl)Amino]Methyl]-1-Methyl-Benzoimidazole-5-Carbonyl]-Pyridin-2-Yl-Amino]Propanoic Acid
- Bibr 953
- Bibr 953Zw
- Dabigatran
- N-(2-(4-(N-(Hexyloxycarbonyl)Amidino)Phenylaminomethyl)-1-Methyl-1H-Benzimidazol-5-Ylcarbonyl)-N-(2-Pyridyl)-Beta-Alanine Ethyl Ester
- N-[[2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-β-alanine
- beta-alanine, N-[[2-[[[4-(aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-
- β-Alanine, N-[[2-[[[4-(aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-
- N-[(2-{[(4-carbamimidoylphenyl)amino]methyl}-1-methyl-1H-ben...
- N-[[2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-beta-alanine
- Dabiga group
- BIBR953;BIBR 953;BIBR-953
- Dabigatran etexilate impurity1513
- 3-[[2-[[(4-carbaMiMidoylphenyl)aMino]Methyl]-1-Met
- BIBR 953 (Dabigatran, Pradaxa)
- Dabigatran(BIB-953
- Dabigatran Q: What is the CAS Number of
- BIB-953
- 3-(2-((4-carbamimidoylphenylamino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoic acid
- BIBR 953(Dabigatran)
- Dabigatran Etexilate Mesilate
- Dabigatran etexilate-1
- Dabigatran base
- 3-[[2-[[(4-carbaMiMidoylphenyl)aMino]Methyl]-1-Methyl-benzoiMidazole-5-carbonyl]-pyridin-2-yl-aMino]
- 3-[[2-[(4-carbamimidoylanilino)methyl]-1-methylbenzimidazole-5-carbonyl]-pyridin-2-ylamino]propanoic
- Dabigatran3-(2-((4-carbamimidoylphenylamino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoic acid
- Dabigatran Ester Impurity B
- Dabigatran API
- BIBR 953;BIBR 953ZW;BIBR953;BIB-953
- Dabigatran Impurity U
- 3-[[2-[(4-carbamimidoylanilino)methyl]-1-methylbenzimidazole-5-carbonyl]-pyridin-2-ylamino]propanoic acid
- 3-[[2-[(4-carbamimidoylanilino)methyl]-1-methylbenzimidazole-5-carbonyl]-pyridin-2-ylamino]propanoic acid Dabigatran (BIBR 953)
- Dabigatran (Acid)
- ethyl 3-(2-(((4-(N'-((hexan-2-yloxy)carbonyl)carbamimidoyl)phenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate
- N-[[2-[[[4-(AMinoiMinoMethyl)phenyl]aMino]Methyl]-1-Methyl-1H-benzo[d]iMidazol-5-yl]carbonyl]-N-pyridin-2-yl-beta-alanine
- DabigatranQ: What is
- Dabigatran (BIBR 953)
- Dabigatran etexilate impurity189
- Dabigatran Impurity b
- N- (2-{ (4-carbaMiMidoylphenyl)aMino Methyl}-1-Met
- Dabigatran Q: What are the applications of
- Dabigatran Q: What is the storage condition of
- Dabigatran USP/EP/BP
- CS-1864
- N-[(2-{[(4-carbaMiMidoylphenyl)aMino]Methyl}-1-Methyl-1HbenziMidazol-
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Dabigatran
CAS:Fórmula:C25H25N7O3Pureza:>95.0%(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:471.523-(2-(((4-Carbamimidoylphenyl)Amino)Methyl)-1-Methyl-N-(Pyridin-2-Yl)-1H-Benzo[D]Imidazole-5-Carboxamido)Propanoic Acid
CAS:3-(2-(((4-Carbamimidoylphenyl)Amino)Methyl)-1-Methyl-N-(Pyridin-2-Yl)-1H-Benzo[D]Imidazole-5-Carboxamido)Propanoic AcidFórmula:C25H25N7O3Pureza:98%Peso molecular:471.51N-Nitroso Dabigatran Etexilate-13C-d3
CAS:Fórmula:C3313CH37D3N8O6Forma y color:White To Off-White SolidPeso molecular:660.75Dabigatran-13C-d3
CAS:Fórmula:C2413CH22D3N7O3Forma y color:White To Off-White SolidPeso molecular:475.53Dabigatran (Standard)
CAS:Dabigatran (Standard) is a reference standard for research and analysis in studies involving Dabigatran. Dabigatran (BIBR 953ZW) is a THROMBIN inhibitor which acts by binding and blocking thrombogenic activity and the prevention of thrombus formation. It is used to reduce the risk of stroke and systemic EMBOLISM in patients with nonvalvular atrial fibrillation.Fórmula:C25H25N7O3Forma y color:SolidPeso molecular:471.5111Ref: IN-DA00I41W
1mg28,00€2mg41,00€5mg50,00€50mg71,00€100mg114,00€250mg135,00€1g282,00€5g714,00€10g1.139,00€Dabigatran
CAS:Applications Nonpeptide, direct thrombin inhibitor. Antithrombotic.
References Hauel, N., et al.: J. Med. Chem., 45, 1757 (2002), Mungall, D., et al.: Curr. Opin. Invest. Drugs, 3, 095 (2002), Stangier, J., et al.: J. Clin. Pharmacol., 45, 555 (2005),Fórmula:C25H25N7O3Forma y color:NeatPeso molecular:471.51Dabigatran-d7 (>90%)
CAS:Producto controladoApplications Dabigatran-d7, is the labeled analogue of Dabigatran (D100090), Nonpeptide, direct thrombin inhibitor. Antithrombotic.
References Hauel, N., et al.: J. Med. Chem., 45, 1757 (2002), Mungall, D., et al.: Curr. Opin. Invest. Drugs, 3, 095 (2002), Stangier, J., et al.: J. Clin. Pharmacol., 45, 555 (2005),Fórmula:C25H18D7N7O3Pureza:>90%Forma y color:NeatPeso molecular:478.55Dabigatran
CAS:Dabigatran (BIBR 953ZW), a thrombin inhibitor, prevents thrombus formation, reducing stroke and embolism risk in nonvalvular atrial fibrillation patients.Fórmula:C25H25N7O3Pureza:97.44% - 98.71%Forma y color:SolidPeso molecular:471.5111Dabigatran
CAS:3-(2-(((4-Carbamimidoylphenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoic acidFórmula:C25H25N7O3Pureza:98%Peso molecular:471.51Dabigatran
CAS:Dabigatran is an oral prodrug that is converted to dabigatran etexilate by esterases in the blood. Dabigatran etexilate is an anticoagulant that inhibits thrombin formation and also prevents the conversion of fibrinogen to fibrin. The drug is used for the prevention of stroke or embolism in people with atrial fibrillation, as well as treatment and prevention of deep venous thrombosis and pulmonary embolism. Dabigatran etexilate has a long half-life of 15-20 hours, meaning that it can be administered once daily. There are two analytical methods for measuring dabigatran concentrations in plasma: one based on the activity of the drug's main metabolite (dabigatran etexilate) and another based on both dabigatran and its active metabolite (dabigatran etexilFórmula:C25H25N7O3Pureza:Min. 95%Forma y color:White PowderPeso molecular:471.51 g/mol
