CAS 2135639-94-8

Fórmula: C27H36N6O3

InChI: InChI=1S/C27H36N6O3/c1-18(19-10-14-35-15-11-19)30-25-22-16-20(6-8-23(22)31-32-26(25)27(34)28-2)21-7-9-24(29-17-21)36-13-5-12-33(3)4/h6-9,16-19H,5,10-15H2,1-4H3,(H,28,34)(H,30,31)/t18-/m0/s1

Clave InChI: SJOFSBIUJPEXTG-SFHVURJKSA-N

SMILES: C[C@@H](C1CCOCC1)NC2=C(N=NC3=C2C=C(C=C3)C4=CN=C(C=C4)OCCCN(C)C)C(=O)NC

AZ 13732641

CAS: 2135639-94-8

AZ 13732641 is a carcinogenic agent that causes DNA damage, leading to the onset of cancer. It is a potent inhibitor of mismatch repair and has been shown to cause lung cancer in rats by inhibiting single-stranded DNA repair. AZ 13732641 also has oncogenic properties and is capable of modifying the spectrum of carcinogens, including hexavalent chromium. This drug has been shown to cause an increase in euchromatin markers, which are associated with tumor suppressors. AZ 13732641 has also been shown to inhibit human cells from dividing, which may be due to its ability to modify histones or activate apoptosis pathways.

Fórmula: C₂₇H₃₆N₆O₃

Pureza: Min. 95%

Peso molecular: 492.6 g/mol

Ref: 3D-KKD63994

ATM Inhibitor-1

CAS: 2135639-94-8

ATM Inhibitor-1 is a highly potent, selective and orally active ATM inhibito (IC50: 0.7 nM) anti-tumor activity.

Fórmula: C₂₇H₃₆N₆O₃

Pureza: 98%

Forma y color: Solid

Peso molecular: 492.61

Ref: TM-T10396