CAS 2140-79-6

2'-O-Metiladenosina

Descripción:

2'-O-Metiladenosina (2′-O-MeA) es un nucleósido modificado derivado de la adenosina, caracterizado por la presencia de un grupo metilo en la posición 2′ del azúcar ribosa. Esta modificación es significativa en varios procesos biológicos, particularmente en la biología del ARN, donde juega un papel en la estabilidad y función de las moléculas de ARN. 2'-O-Metiladenosina se encuentra comúnmente en tRNA y rRNA, contribuyendo a la integridad estructural y al correcto funcionamiento de estas biomoléculas esenciales. La presencia del grupo metilo puede influir en la interacción del ARN con proteínas y otros ácidos nucleicos, afectando procesos como la traducción y el empalme. Además, 2'-O-Metiladenosina es de interés en el estudio de la epitranscriptómica, ya que está involucrado en la regulación de la expresión génica y las respuestas celulares. Su número CAS, 2140-79-6, permite una fácil identificación en bases de datos químicas. En general, 2'-O-Metiladenosina es un componente crucial en el complejo panorama de las modificaciones del ARN, impactando varios aspectos de la función y regulación celular.

Fórmula: C₁₁H₁₅N₅O₄

InChI: InChI=1/C11H15N5O4/c1-19-8-7(18)5(2-17)20-11(8)16-4-15-6-9(12)13-3-14-10(6)16/h3-5,7-8,11,17-18H,2H2,1H3,(H2,12,13,14)/t5-,7-,8-,11-/m1/s1

Clave InChI: InChIKey=FPUGCISOLXNPPC-IOSLPCCCSA-N

SMILES: O(C)[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](CO)[C@H]1O

Sinónimos:

• 2'-O-Methyl-adenosine
• 2'-OMe Adenosine
• Adenosine, 2'-O-methyl-
• Cordysinin B
• 2′-O-Methyladenosine
• (2R,3R,4R,5R)-5-(6-Amino-9H-purin-9-yl)-2-(hydroxymethyl)-4-methoxytetrahydrofuran-3-ol
• 5-(6-aminopurin-9-yl)-2-(hydroxymethyl)-4-methoxyoxolan-3-ol
• 2'-O-Methyl-D-adenosine

2'-O-Methyladenosine

CAS: 2140-79-6

Fórmula: C₁₁H₁₅N₅O₄

Pureza: >98.0%(HPLC)(T)

Forma y color: White to Almost white powder to crystal

Peso molecular: 281.27

Ref: 3B-M2291

2'-O-Methyladenosine, 99%

CAS: 2140-79-6

2'-O-Methyladenosine is an analog of adenosine used to prepare nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the

Fórmula: C₁₁H₁₅N₅O₄

Pureza: 99%

Peso molecular: 281.27

Ref: 02-J64922

2'-O-Methyladenosine

CAS: 2140-79-6

2'-O-Methyladenosine

Fórmula: C₁₁H₁₅N₅O₄

Pureza: 98%

Forma y color: Solid

Peso molecular: 281.27

Ref: 54-OR1010237

2''-O-Methyladenosine

CAS: 2140-79-6

Fórmula: C₁₁H₁₅N₅O₄

Peso molecular: 281.27

Ref: 7W-GE7035

2'-O-Methyladenosine

CAS: 2140-79-6

2'-O-Methyladenosine

Fórmula: C₁₁H₁₅N₅O₄

Pureza: 99.5%

Peso molecular: 281.27

Ref: 54-BUP13241

2'-O-Methyladenosine

CAS: 2140-79-6

Fórmula: C₁₁H₁₅N₅O₄

Pureza: 98%

Forma y color: Solid

Peso molecular: 281.2679

Ref: IN-DA0033F5

2'-O-Methyl Adenosine

Producto controlado

CAS: 2140-79-6

Applications Adenosine analog. Used for preparation of nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase.
References Eldrup, A.B., et al.: J. Med. Chem., 47, 2283 (2004), Shim, J., et al.: Antiviral Res., 243 (2003), Wang, M., et al.: J. Biol. Chem., 278, 9489 (2003),

Fórmula: C₁₁H₁₅N₅O₄

Forma y color: Neat

Peso molecular: 281.27

Ref: TR-M276150

2'-O-Methyladenosine

CAS: 2140-79-6

Fórmula: C₁₁H₁₅N₅O₄

Peso molecular: 281.27

Ref: 4Z-A-267009

2'-O-Methyladenosine

CAS: 2140-79-6

2'-O-Methyladenosine (2'-OMeA) is a nucleoside that is a low-energy analog of adenosine. It has been shown to be an effective inhibitor of protein synthesis in vitro, by inhibiting RNA polymerase in the process of transcription. 2'-OMeA has also been shown to inhibit virus replication in vitro and to have potent inhibitory activity against human immunodeficiency virus type 1 (HIV-1). 2'-OMeA inhibits viral replication by binding to the viral ribonucleotide reductase enzyme and blocking the conversion of ribonucleotides into deoxyribonucleotides. The chemical structures of 2'-OMeA are similar to those found in fatty acids and can be detected using chemical ionization mass spectroscopy. The sequence for 2'-OMeA was determined through sequencing methods including NMR spectroscopy and nuclear magnetic resonance data analysis.

Fórmula: C₁₁H₁₅N₅O₄

Pureza: Min. 98 Area-%

Forma y color: White Off-White Powder

Peso molecular: 281.27 g/mol

Ref: 3D-NM05694

2'-O-Methyladenosine

CAS: 2140-79-6

Fórmula: C₁₁H₁₅N₅O₄

Peso molecular: 281.27

Ref: BE-RMCA066009

2′-O-Methyladenosine

CAS: 2140-79-6

Fórmula: C₁₁H₁₅N₅O₄

Pureza: 98%

Forma y color: Solid

Peso molecular: 281.272

Ref: 10-F225617

(2R,3R,4R,5R)-5-(6-Amino-9H-purin-9-yl)-2-(hydroxymethyl)-4-methoxytetrahydrofuran-3-ol

CAS: 2140-79-6

(2R,3R,4R,5R)-5-(6-Amino-9H-purin-9-yl)-2-(hydroxymethyl)-4-methoxytetrahydrofuran-3-ol

Fórmula: C₁₁H₁₅N₅O₄

Pureza: 98%

Peso molecular: 281.27

Ref: IN-DG19363

2'-O-Methyladenosine

CAS: 2140-79-6

Fórmula: C₁₁H₁₅N₅O₄

Peso molecular: 281.27

Ref: ST-EA-CP-A88041

2'-O-Methyladenosine

CAS: 2140-79-6

2'-O-Methyladenosine, a methylated adenine residue is found in the urine of normals and adenosine deaminase deficient patients.

Fórmula: C₁₁H₁₅N₅O₄

Pureza: 99.89%

Forma y color: White Solid

Peso molecular: 281.2679

Ref: TM-T13482