CAS 2144425-14-7

Fórmula: C17H18F3N5O2

InChI: InChI=1S/C17H18F3N5O2/c1-15(2)8-24(4-3-16(15)13(26)22-14(27)23-16)12-6-10(17(18,19)20)5-11-7-21-9-25(11)12/h5-7,9H,3-4,8H2,1-2H3,(H2,22,23,26,27)

Clave InChI: UBMTZODMRPHSBC-UHFFFAOYSA-N

SMILES: CC1(CN(CCC12C(=O)NC(=O)N2)C3=CC(=CC4=CN=CN34)C(F)(F)F)C

IACS-8968

CAS: 2144425-14-7

IACS-8968

Fórmula: C₁₇H₁₈F₃N₅O₂

Pureza: 98.29%

Peso molecular: 381.35

Ref: 54-PC1028870

IACS-8968

CAS: 2144425-14-7

Pureza: 98.29%

Ref: IN-DA01EOFK

IACS-8968

CAS: 2144425-14-7

IACS-8968 is an imidazole derivative that inhibits the enzyme IDO (indoleamine 2,3-dioxygenase) and kynurenine hydroxylase, which are enzymes involved in the metabolism of tryptophan. This leads to a decrease in the production of kynurenine, which has been shown to have anticancer effects. IACS-8968 can also be used as a chemical inhibitor with other anticancer drugs such as monoclonal antibody or cytotoxic drugs. IACS-8968 has synergistic anticancer properties when combined with other agents.

Fórmula: C₁₇H₁₈F₃N₅O₂

Pureza: Min. 95%

Peso molecular: 381.35 g/mol

Ref: 3D-UKD42514

IACS-8968

CAS: 2144425-14-7

IACS-8968 is a dual IDO and TDO inhibitor (pIC50s: 6.43 for IDO and <5 for TDO).

Fórmula: C₁₇H₁₈F₃N₅O₂

Pureza: 98%

Forma y color: Solid

Peso molecular: 381.35

Ref: TM-T11626