CAS 2162982-11-6

Fórmula: C20H17ClFN3O3

InChI: InChI=1S/C20H17ClFN3O3/c1-12(11-26)23-19(27)17-10-18(13-5-7-14(21)8-6-13)24-25(20(17)28)16-4-2-3-15(22)9-16/h2-10,12,26H,11H2,1H3,(H,23,27)/t12-/m0/s1

Clave InChI: RFGRNBWAUZSMBN-LBPRGKRZSA-N

SMILES: C[C@@H](CO)NC(=O)C1=CC(=NN(C1=O)C2=CC(=CC=C2)F)C3=CC=C(C=C3)Cl

BAY-218

CAS: 2162982-11-6

BAY-218

Fórmula: C₂₀H₁₇ClFN₃O₃

Pureza: ≥98%

Peso molecular: 401.82

Ref: 54-BUP09056

(S)-6-(4-Chlorophenyl)-2-(3-fluorophenyl)-N-(1-hydroxypropan-2-yl)-3-oxo-2,3-dihydropyridazine-4-carboxamide

CAS: 2162982-11-6

Fórmula: C₂₀H₁₇ClFN₃O₃

Pureza: 99%

Peso molecular: 401.8187

Ref: IN-DA01FHMP

BAY-218

CAS: 2162982-11-6

Bindarit (AF2838) is an aryl hydrocarbon receptor (AHR) antagonist.Cost-effective and quality-assured.

Fórmula: C₂₀H₁₇ClFN₃O₃

Pureza: 99.46% - 99.95%

Forma y color: Solid

Peso molecular: 401.819

Ref: TM-T5622

BAY-218

CAS: 2162982-11-6

(S)-6-(4-Chlorophenyl)-2-(3-fluorophenyl)-N-(1-hydroxypropan-2-yl)-3-oxo-2,3-dihydropyridazine-4-carboxamide

Fórmula: C₂₀H₁₇ClFN₃O₃

Pureza: 99%

Peso molecular: 401.82

Ref: IN-DG01082331

(S)-6-(4-Chlorophenyl)-2-(3-fluorophenyl)-N-(1-hydroxypropan-2-yl)-3-oxo-2,3-dihydropyridazine-4-carboxamide

CAS: 2162982-11-6

Fórmula: C₂₀H₁₇ClFN₃O₃

Pureza: ≥99%

Peso molecular: 401.82

Ref: 10-F546155

AHR antagonist 1

CAS: 2162982-11-6

AHR antagonist 1 is a molecule that inhibits the activation of the AHR pathway. It has been shown to inhibit tumor growth in mouse models of cancer. The molecular mechanism of action is not well understood, but it may be due to inhibition of tryptophan metabolism and suppression of kynurenine production. This agent has also been shown to have anti-inflammatory effects through inhibition of the production of IL-1β and TNF-α in macrophages. There are also indications that AHR antagonist 1 may be effective against other types of cancers because it targets a variety of intracellular targets.

Fórmula: C₂₀H₁₇ClFN₃O₃

Pureza: Min. 95%

Peso molecular: 401.82 g/mol

Ref: 3D-MLD98211