CAS 2190490-31-2

Fórmula: C19H16ClFN4O3

InChI: InChI=1S/C19H16ClFN4O3/c1-28-16-8-14-11(7-15(16)25-17(26)4-5-18(25)27)19(23-9-22-14)24-10-2-3-13(21)12(20)6-10/h2-3,6-9,17,26H,4-5H2,1H3,(H,22,23,24)

Clave InChI: YYROAISCXBYHNT-UHFFFAOYSA-N

SMILES: COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)Cl)N4C(CCC4=O)O

1-(4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)-5-hydroxypyrrolidin-2-one (Dacomitinib Impurity)

CAS: 2190490-31-2

1-(4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)-5-hydroxypyrrolidin-2-one (Dacomitinib Impurity)

Fórmula: C₁₉H₁₆ClFN₄O₃

Pureza: 98%

Peso molecular: 402.81

Ref: 54-PC109942

1-(4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)-5-hydroxypyrrolidin-2-one (Dacomitinib Impurity)

CAS: 2190490-31-2

Fórmula: C₁₉H₁₆ClFN₄O₃

Pureza: 98%

Peso molecular: 402.8067

Ref: IN-DA01XG3E

Dacomitinib impurity 3

CAS: 2190490-31-2

Dacomitinib impurity 3 is a contaminant found in Dacomitinib.

Fórmula: C₁₉H₁₆ClFN₄O₃

Peso molecular: 402.81

Ref: TM-TYD-05008

Dacomitinib Impurity 3

CAS: 2190490-31-2

Fórmula: C₁₉H₁₆ClFN₄O₃

Peso molecular: 402.81

Ref: 4Z-D-212007

1-(4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)-5-hydroxypyrrolidin-2-one (Dacomitinib Impurity)

CAS: 2190490-31-2

Pureza: 98%

Peso molecular: 402.81

Ref: 10-F988653

Des-(4-(1-piperidinyl)-2-Butenamide) Dacomitinib-5-hydroxypyrrolidin-2-one

Producto controlado

CAS: 2190490-31-2

Applications Des-(4-(1-piperidinyl)-2-Butenamide) Dacomitinib-5-hydroxypyrrolidin-2-one is a derivative of Dacomitinib (D101575), which is an Erb-inhibitor, or an inhibitor of the members of the epidermal growth factor receptor family. Used as an ant-cancer agent due to observation of over-expressed epidermal growth factor receptor in nearly all cases of squamous cell carcinoma in the head and neck.
References Williams, J. et al.: PLoS., 9, e98557 (2014); Peters, S. et al.: Canc. Treatment Rev., 40, 917 (2014);

Fórmula: C₁₉H₁₆ClFN₄O₃

Forma y color: Neat

Peso molecular: 402.807

Ref: TR-D101275

Dacomitinib Impurity 1

CAS: 2190490-31-2

Fórmula: C₁₉H₁₆ClFN₄O₃

Peso molecular: 402.8

Ref: ST-EA-CP-D72003