CAS 2207569-08-0

Fórmula: C39H33N7O4S

InChI: InChI=1S/C39H33N7O4S/c1-25-42-43-35-24-50-23-32-30(19-26-9-4-2-5-10-26)34(51-39(32)46(25)35)16-14-27-20-40-44(21-27)18-7-3-6-11-28-12-8-13-29-31(28)22-45(38(29)49)33-15-17-36(47)41-37(33)48/h2,4-5,8-10,12-13,20-21,33H,3,7,15,17-19,22-24H2,1H3,(H,41,47,48)

Clave InChI: RTVTYLRQKKDYMQ-UHFFFAOYSA-N

SMILES: CC1=NN=C2N1C3=C(COC2)C(=C(S3)C#CC4=CN(N=C4)CCCC#CC5=C6CN(C(=O)C6=CC=C5)C7CCC(=O)NC7=O)CC8=CC=CC=C8

3-(4-(5-(4-((3-Benzyl-9-methyl-4H,6H-thieno[2,3-e][1,2,4]triazolo[3,4-c][1,4]oxazepin-2-yl)ethynyl)-1H-pyrazol-1-yl)pent-1-yn-1-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione

CAS: 2207569-08-0

3-(4-(5-(4-((3-Benzyl-9-methyl-4H,6H-thieno[2,3-e][1,2,4]triazolo[3,4-c][1,4]oxazepin-2-yl)ethynyl)-1H-pyrazol-1-yl)pent-1-yn-1-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione

Fórmula: C₃₉H₃₃N₇O₄S

Pureza: 99.95%

Peso molecular: 695.79

Ref: 54-OR1134656

3-(4-(5-(4-((3-Benzyl-9-methyl-4H,6H-thieno[2,3-e][1,2,4]triazolo[3,4-c][1,4]oxazepin-2-yl)ethynyl)-1H-pyrazol-1-yl)pent-1-yn-1-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione

CAS: 2207569-08-0

Fórmula: C₃₉H₃₃N₇O₄S

Pureza: 99.95%

Peso molecular: 695.7888

Ref: IN-DA01JWY6

QCA570

CAS: 2207569-08-0

QCA570 is a ubiquitin-protein ligase that belongs to the large family of E3 ligases, which are enzymes that target specific proteins for degradation. QCA570 can deubiquitinate and activate transcriptional factors, such as nuclear hormone receptors, by targeting ubiquitin to their lysine residues. This protein has been shown to be a potential anticancer agent in myeloid leukemia cells. It also inhibits inflammatory diseases and has been shown to inhibit cancer in animal models.

Fórmula: C₃₉H₃₃N₇O₄S

Pureza: Min. 95%

Peso molecular: 695.8 g/mol

Ref: 3D-HND56908

QCA570

CAS: 2207569-08-0

QCA570 is an effective BET degrader based on PROTAC (IC50: 10 nM for BRD4 BD1 Protein).

Fórmula: C₃₉H₃₃N₇O₄S

Pureza: 98%

Forma y color: Solid

Peso molecular: 695.79

Ref: TM-T16701