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CAS 2210298-14-7

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    LCB-2122

    CAS:
    LCB-2122 is an adenosine-like nucleoside analog featuring a C2'-stereoisomeric all-carbon quaternary carbon center. It inhibits doxorubicin-induced myocardial apoptosis with an IC50 value of 0.5 μM and also suppresses imatinib-induced apoptosis. LCB-2122 activates the AMPK signaling pathway, inducing the phosphorylation of AMPK and its downstream substrate acetyl-CoA carboxylase (ACC). Additionally, LCB-2122 alleviates mitochondrial damage caused by doxorubicin and is used in heart failure research.
    Fórmula:C16H25ClN5O7P
    Peso molecular:465.83

    Ref: TM-T214622

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