CAS 22818-40-2

D-p-Hidroxifenilglicina

Descripción:

D-p-Hidroxifenilglicina, con el número CAS 22818-40-2, es un derivado de aminoácido caracterizado por sus componentes fenólicos y glicina. Presenta un grupo hidroxilo (-OH) unido a la posición para del anillo fenílico, lo que contribuye a su solubilidad y reactividad. Este compuesto se estudia a menudo por sus posibles aplicaciones en farmacéuticos, particularmente como un bloque de construcción en la síntesis de diversas moléculas biológicamente activas. D-p-Hidroxifenilglicina exhibe quiralidad, con configuraciones estereoquímicas específicas que influyen en su actividad biológica. Típicamente es un sólido cristalino blanco a blanco sucio, soluble en agua y disolventes orgánicos, lo que lo hace versátil para diversas reacciones químicas. La presencia de grupos funcionales amino y carboxilo le permite participar en reacciones típicas de aminoácidos, como la formación de enlaces peptídicos. Además, sus características estructurales pueden permitir interacciones con receptores biológicos, lo que lo hace de interés en química medicinal y diseño de fármacos. En general, D-p-Hidroxifenilglicina es un compuesto significativo tanto en contextos de química sintética como biológica.

Fórmula: C₈H₉NO₃

InChI: InChI=1S/C8H9NO3/c9-7(8(11)12)5-1-3-6(10)4-2-5/h1-4,7,10H,9H2,(H,11,12)/t7-/m1/s1

Clave InChI: InChIKey=LJCWONGJFPCTTL-SSDOTTSWSA-N

SMILES: [C@@H](C(O)=O)(N)C1=CC=C(O)C=C1

Sinónimos:

• (2R)-2-Amino-2-(4-hydroxyphenyl)acetic acid
• (2R)-2-Azaniumyl-2-(4-hydroxyphenyl)acetate
• (2R)-2-amino-2-phenylethanamide
• (2R)-amino(4-hydroxyphenyl)ethanoic acid
• (R)-(-)-alpha-Amino-(4-hydroxyphenyl)acetic acid
• (R)-(4-Hydroxyphenyl)glycine
• (R)-2-(4-Hydroxyphenyl)glycine
• (R)-2-Amino-2-(4-hydroxyphenyl)acetic acid
• (αR)-α-Amino-4-hydroxybenzeneacetic acid
• 2-(4-Hydroxy-phenyl)glycin D-Form
• 4-Hydroxy-<span class="text-smallcaps">D</span>-phenylglycine
• 4-Hydroxy-D-Phenylglycine
• <span class="text-smallcaps">D</span>-(-)-2-(4-Hydroxyphenyl)glycine
• <span class="text-smallcaps">D</span>-(-)-2-(p-Hydroxyphenyl)glycine
• <span class="text-smallcaps">D</span>-(-)-4-Hydroxyphenylglycine
• <span class="text-smallcaps">D</span>-(-)-Amino(4-hydroxyphenyl)acetic acid
• <span class="text-smallcaps">D</span>-(-)-p-Hydroxyphenylglycine
• <span class="text-smallcaps">D</span>-(-)-α-(4-Hydroxyphenyl)glycine
• <span class="text-smallcaps">D</span>-(-)-α-Amino-4-hydroxyphenylacetic acid
• <span class="text-smallcaps">D</span>-(-)-α-Amino-p-hydroxyphenylacetic acid
• <span class="text-smallcaps">D</span>-2-Amino-2-(p-hydroxyphenyl)acetic acid
• <span class="text-smallcaps">D</span>-α-p-Hydroxyphenylglycine
• Benzeneacetic acid, α-amino-4-hydroxy-, (R)-
• Benzeneacetic acid, α-amino-4-hydroxy-, (αR)-
• D(-)-Alpha-Parahydroxy Phenylglycine
• D(-)4-P-hydroxyphenylglycine
• D-(-)-2-(4-Hydroxyphenyl)Glycine
• D-p-hydroxyphenylglycine
• Glycine, 2-(p-hydroxyphenyl)-, <span class="text-smallcaps">D</span>-
• H-D-Phg(4-OH)-OH
• PH Dane-acid
• p-Hydroxy-(R)-phenylglycine
• p-Hydroxy-<span class="text-smallcaps">D</span>-phenylglycine

4-Hydroxy-D-(-)-2-phenylglycine

CAS: 22818-40-2

Fórmula: C₈H₉NO₃

Pureza: >99.0%(T)(HPLC)

Forma y color: White to Almost white powder to crystal

Peso molecular: 167.16

Ref: 3B-H0758

(-)-4-Hydroxy-D-phenylglycine, 98+%

CAS: 22818-40-2

(-)-4-Hydroxy-D-phenylglycine is used as an organic chemical synthesis intermediate. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item

Fórmula: C₈H₉NO₃

Pureza: 98+%

Forma y color: White to pale cream, Crystals or powder or crystalline powder

Peso molecular: 167.16

Ref: 02-L07190

CEFPROZIL IMPURITY A CRS

CAS: 22818-40-2

CEFPROZIL IMPURITY A CRS

Ref: 41-Y0001372

D-α-(4-HYDROXYPHENYL)GLYCINE CRS

CAS: 22818-40-2

D-α-(4-HYDROXYPHENYL)GLYCINE CRS

Ref: 41-H1430000

D-α-(4-hydroxyphenyl)glycine

CAS: 22818-40-2

D-α-(4-hydroxyphenyl)glycine

Forma y color: White To Off-White

Ref: 47-829

Amoxicillin Related Compound I ((R)-2-Amino-2-(4-hydroxyphenyl)acetic acid)

CAS: 22818-40-2

Aromatic amino-alcohol-phenols, aromatic amino-acid-phenols and other aromatic amino compounds with oxygen function

Fórmula: C₈H₉NO₃

Forma y color: White Crystalline Powder

Peso molecular: 167.05824

Ref: 45-1031591

Benzeneacetic acid, a-amino-4-hydroxy-, (aR)-

CAS: 22818-40-2

Fórmula: C₈H₉NO₃

Pureza: 98%

Forma y color: Solid

Peso molecular: 167.1620

Ref: IN-DA007NPA

Amoxicillin EP Impurity I

CAS: 22818-40-2

Fórmula: C₈H₉NO₃

Forma y color: White To Off-White Solid

Peso molecular: 167.16

Ref: 4Z-A-2310

Cefoperazone Impurity 3

CAS: 22818-40-2

Fórmula: C₈H₉NO₃

Peso molecular: 167.17

Ref: 4Z-C-7810

4-Hydroxy-D-phenylglycine

CAS: 22818-40-2

4-Hydroxy-D-phenylglycine

Fórmula: C₈H₉NO₃

Pureza: 98%

Forma y color: white to off-white powder or crystals or solid

Peso molecular: 167.16g/mol

Ref: 54-OR8733

4-Hydroxy-D-phenylglycine

CAS: 22818-40-2

Fórmula: C₈H₉NO₃

Pureza: ≥ 99.0%

Forma y color: White to off-white crystalline powder

Peso molecular: 167.16

Ref: 7W-GM6146

D-α-(4-Hydroxyphenyl-2,3,56-d4)glycine-α-d1

CAS: 22818-40-2

Fórmula: HOC₆D₄CD(NH₂)COOH

Pureza: 98 atom % D

Peso molecular: 172.08963

Ref: 3U-D7575

D-4-Hydroxyphenylglycine

CAS: 22818-40-2

D-4-Hydroxyphenylglycine is key in making β-lactam antibiotics like Amoxicillin and Cefadroxil.

Fórmula: C₈H₉NO₃

Forma y color: White To Off-White Crystalline Powder

Peso molecular: 167.16

Ref: TM-T39811

Amoxicillin EP Impurity I (Cefadroxil EP Impurity A)

Producto controlado

CAS: 22818-40-2

Fórmula: C₈H₉NO₃

Forma y color: Neat

Peso molecular: 167.16

Ref: 86-MM0232.09

4-Hydroxy-D-(-)-2-phenylglycine

Producto controlado

CAS: 22818-40-2

Impurity Cefadroxil EP Impurity A(Amoxicillin EP Impurity A)
Applications 4-Hydroxy-D-(-)-2-phenylglycine (Cefadroxil EP Impurity A(Amoxicillin EP Impurity A)) is an compound used mainly for the synthetic preparation of β-lactam antibiotics.
References Koide, H., et al.: J. Antibio., 65, 91 (2012); Aranaz, I., et al.: Enzyme. Micro. Tech., 39, 215 (2006);

Fórmula: C₈H₉NO₃

Forma y color: Neat

Peso molecular: 167.16

Ref: TR-H949250

Amoxicillin EP Impurity I

CAS: 22818-40-2

Fórmula: C₈H₉NO₃

Peso molecular: 167.16

Ref: ST-EA-CP-A20009

Cefadroxil EP Impurity A

CAS: 22818-40-2

Fórmula: C₈H₉NO₃

Peso molecular: 167.2

Ref: ST-EA-CP-C61001

p-Hydroxyphenyl glycine HCl

CAS: 22818-40-2

p-Hydroxyphenyl glycine HCl is a model system for an amide and has been shown to inhibit the growth of bacteria. It is also an active analogue of sodium succinate and cyclic peptide, which are glycopeptide antibiotics that have shown activity against gram-positive bacteria such as Streptococcus pneumoniae, Enterococcus faecalis, Staphylococcus aureus, and Bacillus subtilis. The hydroxyl group on p-hydroxyphenyl glycine HCl interacts with hydrogen bonding interactions in the bacterial cell wall, preventing the formation of a covalent bond between the drug molecule and the enzyme cell wall synthesis required for cell wall biosynthesis. This causes inhibition of protein synthesis, leading to cell death by apoptosis.

Fórmula: C₈H₉NO₃·HCl

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 203.62 g/mol

Ref: 3D-FH01618

(R)-2-Amino-2-(4-hydroxyphenyl)acetic acid

CAS: 22818-40-2

Fórmula: C₈H₉NO₃

Pureza: 98%

Forma y color: Solid

Peso molecular: 167.164

Ref: 10-F222543

4-Hydroxy-D-(-)-2-phenylglycine-13C6 (+)-3-Bromo-8-camphorsulfonic Acid

Producto controlado

CAS: 22818-40-2, 5344-58-1, 64933-95-5

Fórmula: C₂C₆H₉NO₃·C₁₀H₁₅BrO₄S

Forma y color: Neat

Peso molecular: 484.31

Ref: TR-H949259