CAS 2320258-95-3

Fórmula: C27H31Cl3F2N6O

InChI: InChI=1S/C27H28F2N6O.3ClH/c28-23-12-18(13-24(29)22(23)17-34-8-10-36-11-9-34)21-2-1-3-25-27(21)33-26(15-31-25)19-14-32-35(16-19)20-4-6-30-7-5-20;;;/h1-3,12-16,20,30H,4-11,17H2;3*1H

Clave InChI: VWBSZLCFZWKXHV-UHFFFAOYSA-N

SMILES: C1CNCCC1N2C=C(C=N2)C3=NC4=C(C=CC=C4N=C3)C5=CC(=C(C(=C5)F)CN6CCOCC6)F.Cl.Cl.Cl

NVP-BSK805 trihydrochloride

CAS: 2320258-95-3

NVP-BSK805 trihydrochloride inhibits JAK2 (0.48 nM IC50); also affects JAK1, JAK3, TYK2.

Fórmula: C₂₇H₃₁Cl₃F₂N₆O

Forma y color: Solid

Peso molecular: 599.93

Ref: TM-T39858

Nvp-bsk805 trihydrochloride

CAS: 2320258-95-3

Nvp-bsk805 trihydrochloride is a small molecule inhibitor, which is synthesized chemically with a specific mode of action targeting the c-Met receptor tyrosine kinase. This compound acts as an ATP-competitive inhibitor, effectively reducing the phosphorylation of c-Met and subsequently disrupting downstream signaling pathways such as MAPK/ERK and PI3K/AKT. These pathways are critical for cellular processes related to growth, survival, and metastasis in cancer cells.

Fórmula: C₂₇H₂₈F₂N₆O·3HCl

Pureza: Min. 95%

Peso molecular: 599.93 g/mol

Ref: 3D-VSD25895