CAS 2328073-61-4

Fórmula: C21H31N5O2

InChI: InChI=1S/C21H31N5O2/c1-13(2)26-9-7-15(8-10-26)22-20-16-11-18(27-3)19(28-4)12-17(16)24-21(25-20)23-14-5-6-14/h11-15H,5-10H2,1-4H3,(H2,22,23,24,25)

Clave InChI: AMAQJTHMSLYMFT-UHFFFAOYSA-N

SMILES: CC(C)N1CCC(CC1)NC2=NC(=NC3=CC(=C(C=C32)OC)OC)NC4CC4

ZT-12-037-01

CAS: 2328073-61-4

ZT-12-037-01

Fórmula: C₂₁H₃₁N₅O₂

Pureza: ≥98%

Peso molecular: 385.5

Ref: 54-BUP04849

N2-Cyclopropyl-N4-(1-isopropylpiperidin-4-yl)-6,7-dimethoxyquinazoline-2,4-diamine

CAS: 2328073-61-4

Fórmula: C₂₁H₃₁N₅O₂

Pureza: 98%

Forma y color: Solid

Peso molecular: 385.5031

Ref: IN-DA01KKFQ

N2-Cyclopropyl-N4-(1-Isopropylpiperidin-4-Yl)-6,7-Dimethoxyquinazoline-2,4-Diamine

CAS: 2328073-61-4

N2-Cyclopropyl-N4-(1-Isopropylpiperidin-4-Yl)-6,7-Dimethoxyquinazoline-2,4-Diamine

Fórmula: C₂₁H₃₁N₅O₂

Pureza: 98%

Peso molecular: 385.5

Ref: 54-OR1023192

ZT-12-037-01

CAS: 2328073-61-4

Zt-12-037-01 is a ATP competitive STK19 inhibitor（IC50 values of 23.96 nM and 27.94 nM for STK19 (WT) and STK19 (D89N),respectively).

Fórmula: C₂₁H₃₁N₅O₂

Pureza: 99.56%

Forma y color: White Solid

Peso molecular: 385.5

Ref: TM-T5597

ZT-12-037-01

CAS: 2328073-61-4

N2-Cyclopropyl-N4-(1-isopropylpiperidin-4-yl)-6,7-dimethoxyquinazoline-2,4-diamine

Fórmula: C₂₁H₃₁N₅O₂

Pureza: 98%

Peso molecular: 385.5

Ref: IN-DG01128455

ZT-12-037-01

CAS: 2328073-61-4

ZT-12-037-01 is a potential drug for the treatment of malignant melanoma. This drug is a phosphoramidate prodrug that is activated by an enzyme known as cytidine deaminase, which converts it to an active form of 5′-fluoro-5′-deoxycytidine. ZT-12-037-01 has been shown to inhibit the growth of malignant melanoma cells, and also induces cell death in these cells. ZT-12-037-01 also inhibits tumor progression in mice with preclinical models of cancer and research on this drug has helped advance our understanding of this disease.

Fórmula: C₂₁H₃₁N₅O₂

Pureza: Min. 95%

Peso molecular: 385.5 g/mol

Ref: 3D-DTD07361