CAS 23720-80-1

Nardosinona

Descripción:

Nardosinona es un compuesto sesquiterpeno natural derivado principalmente de la planta Nardostachys jatamansi, comúnmente conocida como espikenardo. Se caracteriza por su compleja estructura bicíclica, que contribuye a sus propiedades químicas únicas. Nardosinona exhibe una variedad de actividades biológicas, incluyendo efectos antiinflamatorios, antimicrobianos y potenciales efectos neuroprotectores, lo que lo hace de interés en la investigación farmacológica. El compuesto se encuentra típicamente en aceites esenciales y extractos de la planta, y su presencia a menudo se asocia con prácticas medicinales tradicionales. En términos de solubilidad, Nardosinona es generalmente más soluble en disolventes orgánicos que en agua, lo cual es común para muchos terpenoides. Su estructura molecular incluye múltiples grupos funcionales que pueden participar en diversas reacciones químicas, mejorando sus aplicaciones potenciales tanto en la química de productos naturales como en el desarrollo terapéutico. En general, Nardosinona representa un compuesto significativo dentro del ámbito de los productos naturales, con estudios en curso destinados a elucidar su rango completo de efectos biológicos y usos potenciales en medicina.

Fórmula: C₁₅H₂₂O₃

InChI: InChI=1S/C15H22O3/c1-9-6-5-7-10-11(16)8-12-13(15(9,10)4)14(2,3)18-17-12/h7,9,12-13H,5-6,8H2,1-4H3/t9-,12-,13+,15+/m1/s1

Clave InChI: InChIKey=KXGHHSIMRWPVQM-JWFUOXDNSA-N

SMILES: C[C@@]12[C@]3([C@@](CC(=O)C1=CCC[C@H]2C)(OOC3(C)C)[H])[H]

Sinónimos:

• (3aR,9R,9aR,9bS)-1,1,9,9a-tetramethyl-1,3a,4,7,8,9,9a,9b-octahydro-5H-naphtho[2,1-c][1,2]dioxol-5-one
• (3aR,9R,9aR,9bS)-1,3a,4,7,8,9,9a,9b-Octahydro-1,1,9,9a-tetramethyl-5H-naphtho[2,1-c][1,2]dioxol-5-one
• 5H-Naphtho[2,1-c][1,2]dioxol-5-one, 1,3a,4,7,8,9,9a,9b-octahydro-1,1,9,9a-tetramethyl-, (3aR,9R,9aR,9bS)-
• 5H-Naphtho[2,1-c][1,2]dioxol-5-one, 1,3a,4,7,8,9,9a,9b-octahydro-1,1,9,9a-tetramethyl-, [3aR-(3aα,9α,9aα,9bα)]-
• Nardosinon
• Nardosinone

NARDOSINONE

CAS: 23720-80-1

Fórmula: C₁₅H₂₂O₃

Pureza: 98%

Forma y color: Solid

Peso molecular: 250.3334

Ref: IN-DA00C4G3

Nardosinone

CAS: 23720-80-1

Nardosinone

Pureza: ≥98%

Peso molecular: 250.33g/mol

Ref: 54-BUP05640

Nardosinone

CAS: 23720-80-1

Nardosinone

Pureza: 98%

Peso molecular: 250.33g/mol

Ref: 54-OR1024412

Nardosinone

CAS: 23720-80-1

Fórmula: C₁₅H₂₂O₃

Peso molecular: 250.34

Ref: 7W-GY9891

Nardosinone

CAS: 23720-80-1

Nardosinone is an enhancer of nerve growth factor and possesses a wide range of pharmacological effects, including sedative, adaptogen-like, anti-depressive, anti-leukemic, anti-tumorous, and anti-trypanosomal activities. It has a wide spectrum of targets including PI3K,Akt,MEK,ERK, PKA, MAPK.

Fórmula: C₁₅H₂₂O₃

Pureza: 95%~99%

Peso molecular: 250.338

Ref: BP-BP0980

Nardosinone

CAS: 23720-80-1

Nardosinone inhibits H9c2 cell hypertrophy, protects neurons from OGD, and boosts neurite outgrowth by modifying key signaling pathways.

Fórmula: C₁₅H₂₂O₃

Pureza: 98.82% - 99%

Forma y color: Solid

Peso molecular: 250.33

Ref: TM-T6S1740

Nardosinone

CAS: 23720-80-1

Oxygen-heterocyclic compound

Fórmula: C₁₅H₂₂O₃

Pureza: ≥ 98.0 % (HPLC)

Forma y color: Crystals

Peso molecular: 250.34

Ref: 5G-83526

NARDOSINONE

CAS: 23720-80-1

Pureza: ≥98%

Peso molecular: 250.3379974

Ref: 10-F859800

Nardosinone

Producto controlado

CAS: 23720-80-1

Applications Nardosinone reduces neuronal injury and protects H9c2 cardiac cells from angiotensin II-induced hypertrophy which may give rise to heart failure. Enhancer of nerve growth factor (NGF).
References Du, M. et al.: J. Huazhong Uni. Sci. Tech. Med. Serv., 33, 822 (2013); Li, P. et al.: Dev. Brain Res., 145, 177 (2003);

Fórmula: C₁₅H₂₂O₃

Forma y color: White To Off-White

Peso molecular: 250.33

Ref: TR-N378930

Nardosinone

Producto controlado

CAS: 23720-80-1

Nardosinone is a secoiridoid compound, which is a natural product derived from the roots of the plant Nardostachys jatamansi, commonly known as spikenard. The source of Nardosinone is a flowering plant that is native to the Himalayan region and has been traditionally used in Ayurvedic medicine for its therapeutic properties. The mode of action of Nardosinone involves modulation of neurotransmitter systems, inhibition of neuroinflammation, and protection against oxidative damage, contributing to its neuroprotective effects. Nardosinone exhibits potential applications in the treatment of neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease, due to its ability to improve cognitive function and mitigate neuronal damage. Additionally, it is being investigated for its potential role in mood regulation and anti-anxiety effects. Given its intriguing pharmacological profile, Nardosinone is the subject of ongoing research aimed at understanding its comprehensive mechanisms and potential therapeutic benefits in neuroscience.

Fórmula: C₁₅H₂₂O₃

Pureza: Min. 95%

Forma y color: Solid

Peso molecular: 250.33 g/mol

Ref: 3D-FN73909