CAS 2374772-60-6

Fórmula: C23H17FN6S2

InChI: InChI=1S/C23H17FN6S2/c1-14-4-2-7-20(25-14)23-18(15-8-9-19-21(10-15)29-32-28-19)12-30(27-23)13-22(31)26-17-6-3-5-16(24)11-17/h2-12H,13H2,1H3,(H,26,31)

Clave InChI: TVWMUKRZUMLJMU-UHFFFAOYSA-N

SMILES: CC1=NC(=CC=C1)C2=NN(C=C2C3=CC4=NSN=C4C=C3)CC(=S)NC5=CC(=CC=C5)F

J-1048

CAS: 2374772-60-6

J-1048, an activin receptor-like kinase 5 (ALK5) inhibitor, effectively suppresses TAA-induced liver fibrosis in mice through specific inhibition of the TGF-β/

Fórmula: C₂₃H₁₇FN₆S₂

Forma y color: Solid

Peso molecular: 460.55

Ref: TM-T78790