CAS 2415-24-9
:Catalpol
Descripción:
Catalpol, con el número CAS 2415-24-9, es un glucósido iridoide que se encuentra de forma natural principalmente en varias especies de plantas, particularmente en el género Rehmannia. Se caracteriza por su estructura química, que incluye un moiety de glucosa unido a un núcleo iridoide. Catalpol es conocido por sus posibles propiedades farmacológicas, incluyendo efectos antiinflamatorios, antioxidantes y neuroprotectores. Se ha estudiado por su papel en la medicina tradicional, particularmente en remedios herbales chinos, donde se cree que apoya la salud renal y mejora la vitalidad general. El compuesto exhibe solubilidad en disolventes polares, lo cual es típico de los glucósidos, y su estabilidad puede verse influenciada por factores como el pH y la temperatura. La investigación sobre Catalpol continúa explorando sus mecanismos de acción y posibles aplicaciones terapéuticas, convirtiéndolo en un tema de interés tanto en la farmacognosia como en la química medicinal.
Fórmula:C15H22O10
InChI:InChI=1S/C15H22O10/c16-3-6-9(19)10(20)11(21)14(23-6)24-13-7-5(1-2-22-13)8(18)12-15(7,4-17)25-12/h1-2,5-14,16-21H,3-4H2/t5-,6-,7-,8+,9-,10+,11-,12+,13+,14+,15-/m1/s1
Clave InChI:InChIKey=LHDWRKICQLTVDL-PZYDOOQISA-N
SMILES:C(O)[C@@]12[C@@]3([C@]([C@H](O)[C@@]1(O2)[H])(C=CO[C@H]3O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[H])[H]
Sinónimos:- (1AS-(1aalpha,1bbeta,2beta,5abeta,6beta,6aalpha))-1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno(4,5)cyclopenta(1,2-c)pyran-2-yl-beta-D-glucopyranoside
- (1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-Hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl β-<span class="text-smallcaps">D</span>-glucopyranoside
- (1aS,1bS,2S,5aR,6S,6aS)-6-hydroxy-1a-(hydroxymethyl)-1a,1b,2,5a,6,6a-hexahydrooxireno[4,5]cyclopenta[1,2-c]pyran-2-yl beta-D-glucopyranoside
- 6-Hydroxy-1A-(Hydroxymethyl)-1A,1B,2,5A,6,6A-Hexahydrooxireno[4,5]Cyclopenta[1,2-C]Pyran-2-Yl Hexopyranoside
- 7,8-Epoxyaucubin
- Aucubin 7,8-epoxide
- Catalpinoside
- Catalposide, des-p-hydroxybenzoyl-
- Catapol
- De(p-hydroxybenzoyl)catalposide
- beta-D-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-6-hydroxy- 1a-(hydroxymethyl)oxireno(4,5)cyclopenta(1,2-c)pyran-2-yl, (1aS-(1a-alpha,1b-beta,2-beta,5a-beta,6-beta,6a-alpha))-
- beta-D-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno(4,5)cyclopenta(1,2-c)pyran-2-yl, (1aS-(1aalpha,1bbeta,2beta,5abeta,6beta,6aalpha))-
- β-<span class="text-smallcaps">D</span>-Glucopyranoside, (1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl
- β-<span class="text-smallcaps">D</span>-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl, [1aS-(1aα,1bβ,2β,5aβ,6β,6aα)]-
- Catalpol
- β-D-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl, [1aS-(1aα,1bβ,2β,5aβ,6β,6aα)]-
- β-D-Glucopyranoside, (1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl
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Se han encontrado 16 productos.
Catalpol
CAS:Fórmula:C15H22O10Pureza:>95.0%(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:362.33(1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-Hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl β-D-glucopyranoside
CAS:Fórmula:C9H16O4Pureza:98%Forma y color:SolidPeso molecular:188.2209Catalpol
CAS:Catalpol (Catalpinoside) is an iridoid glycoside with neuroprotective, anti-inflammatory, and anti-hepatitis virus effects.Fórmula:C15H22O10Pureza:99.74% - 99.89%Forma y color:SolidPeso molecular:362.33Catalpol
CAS:Fórmula:C15H22O10Pureza:≥ 96.5%Forma y color:White, off-white or faint brown powderPeso molecular:362.33Catalpol
CAS:Catalpol analytical standard provided with w/w absolute assay, to be used for quantitative titration.Fórmula:C15H22O10Pureza:(HPLC) ≥99%Forma y color:PowderPeso molecular:362.34Catalpol
CAS:Catalpol, an iridoid glucoside, has been reported to inhibit apoptosis of neuron and endothelial cells; the pretreatment of H9c2 cells with catalpol can be against H 2 O 2 -induced apoptosis, and the protective effect of catalpol involves the mitochondrial-dependent caspase pathway and is associated with increased Bcl-2 and decreased Bax expression.Fórmula:C15H22O10Pureza:95%~99%Forma y color:PowderPeso molecular:362.331Catalpol
CAS:(2S,3R,4S,5S,6R)-2-(((1aS,1bS,2S,5aR,6S,6aS)-6-Hydroxy-1a-(hydroxymethyl)-1a,1b,2,5a,6,6a-hexahydrooxireno[2',3':4,5]cyclopenta[1,2-c]pyran-2-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triolFórmula:C15H22O10Pureza:98%Peso molecular:362.33Catalpol
CAS:Natural glycosideFórmula:C15H22O10Pureza:≥ 98.0 % (HPLC)Forma y color:PowderPeso molecular:362.33Catapol
CAS:Applications Catapol is an iridoid glucoside that has been shown to alleviate neuropathic pain.
References Gong, N. et al.: Neuripharmacol., 83, 31 (2014); Liu, Z. et al.: Curr. Bioact. COmp., 9, 306 (2013);Fórmula:C15H22O10Forma y color:NeatPeso molecular:362.33Catalpol
CAS:Catalpol is an iridoid glycoside, which is a natural compound isolated primarily from the roots of the plant *Rehmannia glutinosa*. This compound is known for its various bioactive properties, functioning predominantly through its ability to modulate antioxidant pathways, regulate inflammatory responses, and exert neuroprotective effects. These modes of action are attributed to its capacity to influence cellular signaling pathways, such as the PI3K/Akt pathway, and to interact with reactive oxygen species (ROS), thereby mitigating oxidative stress.Fórmula:C15H22O10Pureza:Min. 95%Forma y color:PowderPeso molecular:362.33 g/mol
![(1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-Hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopen…](https://static.cymitquimica.com/products/IN/thumb/DA0039M9.jpg)
