CAS 2421118-05-8

JKE-1716

CAS: 2421118-05-8

JKE-1716

Fórmula: C₂₀H₂₀Cl₂N₄O₄

Pureza: 98.0%

Peso molecular: 451.3

Ref: 54-OR1111076

JKE-1716

CAS: 2421118-05-8

Pureza: 98.0%

Ref: IN-DA01LINX

JKE-1716

CAS: 2421118-05-8

JKE-1716 is an inhibitor of glutathione peroxidase 4 (GPX4) and a derivative of the GPX4 inhibitor ML-210 .1JKE-1716 reduces viability of LOX-IMVI cancer cells in a concentration-dependent manner and in a panel of additional cancer cell lines, an effect that can be blocked by the ferroptosis inhibitor ferrostatin-1 . 1.Eaton, J.K., Furst, L., Ruberto, R.A., et al.Selective covalent targeting of GPX4 using masked nitrile-oxide electrophilesNat. Chem. Biol.16(5)497-506(2020)

Fórmula: C₂₀H₂₀Cl₂N₄O₄

Forma y color: Solid

Peso molecular: 451.3

Ref: TM-T37805

JKE-1716

CAS: 2421118-05-8

JKE-1716 is a peptide with the amino acid sequence Tyr-Glu-Arg-Lys. It is an activator of ion channels and can be used in research as a tool for studying the function of ion channels. JKE-1716 has been shown to inhibit the binding of ligands to receptors, which can be used to study protein interactions and pharmacology. JKE-1716 has been shown to have high purity, which makes it useful as a research tool that is not contaminated with other proteins or compounds.

Fórmula: C₂₀H₂₀Cl₂N₄O₄

Pureza: Min. 95%

Peso molecular: 451.3 g/mol

Ref: 3D-WWD11805