CAS 2436473-55-9

Fórmula: C27H31FN10O2

InChI: InChI=1S/C27H31FN10O2/c1-17-12-22(32-23-13-18(2)34-35-23)33-26(31-17)36-8-6-27(7-9-36)25(39)37(10-11-40-27)19(3)20-4-5-24(29-14-20)38-16-21(28)15-30-38/h4-5,12-16,19H,6-11H2,1-3H3,(H2,31,32,33,34,35)/t19-/m0/s1

Clave InChI: DIMALNWQSQDLJJ-IBGZPJMESA-N

SMILES: CC1=CC(=NN1)NC2=NC(=NC(=C2)C)N3CCC4(CC3)C(=O)N(CCO4)[C@@H](C)C5=CN=C(C=C5)N6C=C(C=N6)F

RET-IN-4

CAS: 2436473-55-9

RET-IN-4: Oral RET inhibitor, IC50 ~1 nM for variants. Selective over JAK2/FLT3. Potent anticancer use.

Fórmula: C₂₇H₃₁FN₁₀O₂

Forma y color: Solid

Peso molecular: 546.611

Ref: TM-T40097