CAS 24697-74-3

Leonurina

Descripción:

Leonurina, con el número CAS 24697-74-3, es un alcaloide que se encuentra de forma natural, derivado principalmente de la planta Leonurus cardiaca, comúnmente conocida como hierba madre. Este compuesto se caracteriza por sus características estructurales, que incluyen un anillo de piridina y un grupo hidroxilo fenólico, que contribuyen a su actividad biológica. Leonurina es conocido por sus posibles propiedades farmacológicas, incluyendo efectos antiinflamatorios, antioxidantes y neuroprotectores. Se ha estudiado por sus posibles aplicaciones en la medicina tradicional, particularmente en el tratamiento de trastornos cardiovasculares y neurológicos. Además, Leonurina exhibe efectos sedantes leves, que pueden ser beneficiosos para la ansiedad y el alivio del estrés. Su solubilidad en agua es limitada, lo que puede afectar su biodisponibilidad y eficacia terapéutica. A medida que la investigación continúa, se está explorando todo el espectro de sus efectos y mecanismos de acción, destacando la importancia de los compuestos naturales en el desarrollo de medicamentos y aplicaciones terapéuticas.

Fórmula: C₁₄H₂₁N₃O₅

InChI: InChI=1S/C14H21N3O5/c1-20-10-7-9(8-11(21-2)12(10)18)13(19)22-6-4-3-5-17-14(15)16/h7-8,18H,3-6H2,1-2H3,(H4,15,16,17)

Clave InChI: InChIKey=WNGSUWLDMZFYNZ-UHFFFAOYSA-N

SMILES: C(OCCCCNC(=N)N)(=O)C1=CC(OC)=C(O)C(OC)=C1

Sinónimos:

• 24697-74-3
• 4-Carbamimidamidobutyl 4-Hydroxy-3,5-Dimethoxybenzoate Hydrochloride Hydrate
• 4-Carbamimidamidobutyl-4-hydroxy-3,5-dimethoxybenzolcarboxylat
• 4-Guanidino-1-butanol Syringate
• 4-Hydroxy-3,5-dimethoxybenzoic Acid 4-[(Aminoiminomethyl)amino]butyl Ester
• 4-Hydroxy-3,5-dimethoxybenzoic Acid d-Guanidinobutyl Ester
• 4-[(Diaminomethylidene)Amino]Butyl 4-Hydroxy-3,5-Dimethoxybenzoate
• Benzoic Acid, 4-Hydroxy-3,5-Dimethoxy-, 4-[(Aminoiminomethyl)Amino]Butyl Ester
• Benzoic acid, 4-hydroxy-3,5-dimethoxy-, ester with (4-hydroxybutyl)guanidine
• Guanidine, (4-hydroxybutyl)-, 4-hydroxy-3,5-dimethoxybenzoate
• Guanidine, (4-hydroxybutyl)-, 4-hydroxy-3,5-dimethoxybenzoate (ester)
• Leonurin
• Leonurine
• Scm 198
• Syringic Acid d-Guanidinobutyl Ester

Leonurine

CAS: 24697-74-3

Leonurine

Fórmula: C₁₄H₂₁N₃O₅

Pureza: ≥98%

Peso molecular: 311.33

Ref: 54-BUP10292

4-Guanidinobutyl 4-Hydroxy-3,5-Dimethoxybenzoate

CAS: 24697-74-3

4-Guanidinobutyl 4-Hydroxy-3,5-Dimethoxybenzoate

Fórmula: C₁₄H₂₁N₃O₅

Pureza: 99+%

Peso molecular: 311.33

Ref: 54-OR1027299

Leonurine

CAS: 24697-74-3

Fórmula: C₁₄H₂₂CLN₃O₅

Peso molecular: 347.80

Ref: 7W-GY7471

Leonurine

CAS: 24697-74-3

Leonurine hydrochloride has anti-oxidative, anti-inflammatory, and antitumor activities, it exerts antidiabetic, cardiovascular, and bovine mastitis protection, it has an inhibitory effect on bleeding caused by incomplete abortion. Leonurine hydrochloride increases the expression levels of caspase-3, caspase-9 and Bax/Bcl-2, and it inhibits osteoclastogenesis and prevent osteoporosis associated with estrogen deficiency by inhibiting the NF-κB and PI3K/Akt signaling pathways.

Fórmula: C₁₄H₂₁N₃O₅

Pureza: 95%~99%

Peso molecular: 311.338

Ref: BP-BP0850

Leonurine

CAS: 24697-74-3

4-Guanidinobutyl 4-hydroxy-3,5-dimethoxybenzoate

Fórmula: C₁₄H₂₁N₃O₅

Pureza: 99+%

Peso molecular: 311.33

Ref: IN-DG165143

Leonurine

CAS: 24697-74-3

Leonurine (SCM-198) is an alkaloid that has been found in H. leonuri and with anti-oxidative and anti-inflammatory.

Fórmula: C₁₄H₂₂ClN₃O₅

Pureza: 98.55%

Forma y color: Solid

Peso molecular: 347.795

Ref: TM-T5S2102

Leonurine

Producto controlado

CAS: 24697-74-3

Applications Leonurine is a pseudoalkaloid that has been isolated from Leonotis leonurus. A natural product with antioxidant, anti-inflammatory and cardioprotective properties for the treatment of wild variety of conditions including stroke, cerebral thrombosis and cardiovascular diseases.
References He, C., et al.: Zhongguo Linchuang Yaolixue Yu Zhiliaoxue, 18, 1419 (2013); Nsuala, B. N., et al.: J. Ethnopharmacol., 174, 520 (2015); Sun, Y., et al.; Eur. J. Drug Metabo. Pharmacokinet., 41, 423 (2016)

Fórmula: C₁₄H₂₁N₃O₅

Forma y color: Neat

Peso molecular: 311.33

Ref: TR-L329603

Leonurine

CAS: 24697-74-3

Leonurine is a polyphenolic compound that belongs to the group of natural compounds. It has been shown to have neuroprotective effects in vitro by inhibiting neuronal death at low doses. Leonurine also blocks the oxidative injury pathway, which may be related to its ability to inhibit apoptosis and reduce atherosclerotic lesion size in mice. In addition, leonurine inhibits the p-hydroxybenzoic acid (PHBA) oxidation pathway, which may contribute to its anti-inflammatory activities. Leonurine binds with high affinity and specificity to toll-like receptor 4 (TLR4), which may be related to its immunosuppressive properties.

Pureza: Min. 95%

Ref: 3D-FL73876

Leonurine

CAS: 24697-74-3

Fórmula: C₁₄H₂₁N₃O₅

Pureza: %

Forma y color: Solid

Peso molecular: 311.3336

Ref: IN-DA002P1O