CAS 25812-30-0
:gemfibrozilo
Descripción:
gemfibrozilo es un medicamento que se utiliza principalmente para reducir los niveles de lípidos en pacientes con hiperlipidemia, particularmente para reducir los triglicéridos y aumentar el colesterol de lipoproteínas de alta densidad (HDL). Pertenece a la clase de medicamentos conocidos como fibratos y actúa activando el receptor alfa activado por proliferadores de peroxisomas (PPARα), lo que mejora la oxidación de ácidos grasos y disminuye la producción de triglicéridos en el hígado. Químicamente, gemfibrozilo se caracteriza por su fórmula molecular, que incluye átomos de carbono, hidrógeno y oxígeno, y tiene una configuración estructural específica que contribuye a su actividad farmacológica. La sustancia se administra típicamente por vía oral y se absorbe bien en el tracto gastrointestinal. Su farmacocinética implica un metabolismo extenso en el hígado, principalmente a través de la glucuronidación, y tiene una vida media relativamente larga, lo que permite una dosificación dos veces al día. Los efectos secundarios comunes pueden incluir trastornos gastrointestinales, y está contraindicado en pacientes con enfermedad hepática o renal severa. Al igual que con cualquier medicamento, es esencial monitorear los niveles de lípidos y las posibles interacciones medicamentosas durante el tratamiento.
Fórmula:C15H22O3
InChI:InChI=1/C15H22O3/c1-11-6-7-12(2)13(10-11)18-9-5-8-15(3,4)14(16)17/h6-7,10H,5,8-9H2,1-4H3,(H,16,17)
Clave InChI:InChIKey=HEMJJKBWTPKOJG-UHFFFAOYSA-N
SMILES:O(CCCC(C(O)=O)(C)C)C1=C(C)C=CC(C)=C1
Sinónimos:- 2,2-Dimethyl-5-(2,5-dimethylphenoxy)pentanoic acid
- 2,2-Dimethyl-5-(2,5-dimethylphenoxy)valeriansaeure
- 2,2-Dimethyl-5-(2,5-xylyloxy)valeriansaeure
- 2,2-Dimethyl-5-(2,5-xylyloxy)valeric acid
- 5-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoic acid
- 5-[(2,5-Dimethylphenyl)oxy]-2,2-dimethylpentanoic acid
- Apo-Gemfibrozil
- Ausgem
- Bolutol
- Brn 1881200
- Brozil
- Ccris 318
- Cholespid
- Ci 719
- Clearol
- Decrelip
- Elmogan
- Fetinor
- Fibratol
- Fibrocit
- Gem-S
- Gemd
- Gemfibril
- Gemfibromax
- Gemfibrozil [USAN:INN:BAN]
- Gemfibrozilo
- Gemfibrozilo [INN-Spanish]
- Gemfibrozilum
- Gemfibrozilum [INN-Latin]
- Gemlipid
- Gemnpid
- Genlip
- Gevilon
- Gevilon Uno
- Gozid
- Hidil
- Hipolixan
- Hsdb 7735
- Innogen
- Ipolipid
- Jezil
- Lanaterom
- Lifibron
- Lipazil
- Lipigem
- Lipira
- Lipizyl
- Lipur
- Litarek
- Lopid
- Lopizid
- Low-Lip
- Micolip
- Normolip
- Pentanoic acid, 5-(2,5-dimethylphenoxy)-2,2-dimethyl-
- Pilder
- Polyxit
- Progemzal
- Reducel
- Regulip
- Renabrazin
- Sinelip
- Synbrozil
- Taborcil
- Tentroc
- Trialmin
- Trialmin 900
- Unii-Q8X02027X3
- Valeric acid, 2,2-dimethyl-5-(2,5-xylyloxy)-
- WL-Gemfibrozil
- Gemfibrozil
- 5-(2,5-DIMETHYLPHENOXY)-2,2-DIMETHYLPENTANOICACID(GEMFIBROZIL)
- GEMFIBROZIL,USP
- 2,2-DIMETHYL-5-[2,5-DIMETHYL-PHENOXY]PENTANOIC ACID
- 5-(2,5-dimethylphenoxy)-2,2-dimethyl-pentanoicaci
- 5-(2,5-DIMETHYLPHYLPHENOXY)-2,2-DIMETHYLPENTANOIC ACID
- Lipozid
- 2,2-dimethyl-5-(2,5-xylyloxy)-valericaci
- 5-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoic Acid, CI-719, Decrelip, Genlip, Gevilon, Lipozid, Lpur, Lopid
- Gemcitabine intermediates
- 5-(2,5-Dimethylphenoxy)-2,2-DimethylpentamoicAcid
- 2,2-Dimethyl-5-(2,5-Dimethylphenoxy)Valeric
- CI-7
- Ver más sinónimos
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Encontrado 19 productos.
Gemfibrozil
CAS:Fórmula:C15H22O3Pureza:>98.0%(GC)(T)Forma y color:White to Almost white powder to crystalPeso molecular:250.34GEMFIBROZIL FOR SYSTEM SUITABILITY CRS
CAS:GEMFIBROZIL FOR SYSTEM SUITABILITY CRSFórmula:C15H22O3Peso molecular:250.3334GEMFIBROZIL CRS
CAS:GEMFIBROZIL CRSFórmula:C15H22O3Forma y color:Waxy. Crystalline Powder. White. Powder.Peso molecular:250.3334Gemfibrozil
CAS:GemfibrozilFórmula:C15H22O3Pureza:99.9%Forma y color:White SolidPeso molecular:250.15689Gemfibrozil
CAS:Carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides etc not elsewhere specified or includedFórmula:C15H22O3Forma y color:Off-White White PowderPeso molecular:250.15689Gemfibrozil
CAS:Gemfibrozil, a fibric acid derivative, stimulates PPARalpha, boosts fatty acid oxidation, LPL, lowers VLDL-C, apoC-III, and raises HDL-C.Fórmula:C15H22O3Pureza:99.53% - 99.88%Forma y color:Crystals From Hexane SolidPeso molecular:250.335-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoic acid
CAS:Fórmula:C15H22O3Pureza:98%Forma y color:SolidPeso molecular:250.3334Gemfibrozil
CAS:Fórmula:C15H22O3Pureza:≥ 98.0% (anhydrous basis)Forma y color:White crystalline powderPeso molecular:250.33Gemfibrozil 100 µg/mL in Acetonitrile
CAS:Fórmula:C15H22O3Forma y color:Single SolutionPeso molecular:250.33Gemfibrozil
CAS:Producto controlado<p>Applications A serum lipid regulating agent used as an antihyperlipoproteinemic.This compound is a contaminant of emerging concern (CECs).<br>References Kissebach, A.H., et al.: Atherosclerosis, 24, 199 (1976), Lewis, J.E., et al.: Pract. Cardiol., 9, 99 (1983), Rubins, H.B., et al.: N. Engl. J. Med., 341, 410 (1999)<br></p>Fórmula:C15H22O3Forma y color:NeatPeso molecular:250.33Gemfibrozil
CAS:<p>Gemfibrozil is a chemical inhibitor that inhibits the response element to the transcription factor PPAR-α. It has been shown to decrease cardiac effects such as increased heart rate, stroke volume, and cardiac output. Gemfibrozil has been used for wastewater treatment and has been found to be an analytical method for determining the concentration of other drugs in urine. The ecological effects of gemfibrozil are not well understood, but it is known that it can cause adverse effects on locomotor activity in animals. Gemfibrozil is a potent inducer of liver enzymes and may interact with other drugs by increasing their concentration time curve. This drug also has oral hypoglycemic properties, which lowers the blood glucose level by stimulating insulin production.</p>Fórmula:C15H22O3Pureza:Min. 95%Peso molecular:250.33 g/mol5-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoic acid
CAS:Fórmula:C15H22O3Pureza:98%Forma y color:Crystalline PowderPeso molecular:250.338
