CAS 2603528-97-6

ART558

CAS: 2603528-97-6

ART558

Fórmula: C₂₁H₂₁F₃N₄O₂

Pureza: ≥98%

Peso molecular: 418.41

Ref: 54-BUP01029

ART558

CAS: 2603528-97-6

ART558 is a potent, selective, low molecular weight, allosteric DNA polymerase activity of Polθ inhibitor (IC50=7.9 nM).

Fórmula: C₂₁H₂₁F₃N₄O₂

Pureza: 99.18% - 99.67%

Forma y color: Solid

Peso molecular: 418.41

Ref: TM-T9275

ART558

CAS: 2603528-97-6

(2S,3R)-1-(3-Cyano-6-methyl-4-(trifluoromethyl)pyridin-2-yl)-3-hydroxy-N-methyl-N-(m-tolyl)pyrrolidine-2-carboxamide

Fórmula: C₂₁H₂₁F₃N₄O₂

Pureza: 98%

Peso molecular: 418.41

Ref: IN-DG01373206

ART558

CAS: 2603528-97-6

ART558 is a potent inhibitor of kinases, specifically targeting cyclin-dependent kinases (CDKs). It has been extensively studied for its potential use in cancer treatment. ART558 works by inhibiting the activity of CDKs, which are proteins that regulate cell division and growth. This inhibition leads to apoptosis, or programmed cell death, in cancer cells. ART558 has shown promising results in preclinical studies against a variety of human cancers, including lung and breast tumors. Additionally, it has been found to be effective against Chinese hamster ovary cells and other tumor cells. ART558 is being developed as an anticancer drug candidate due to its medicinal properties and potential as a targeted therapy for cancer patients.

Fórmula: C₂₁H₂₁F₃N₄O₂

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 418.4 g/mol

Ref: 3D-DEE52897