CAS 2640292-52-8

Fórmula: C22H17N3O2S

InChI: InChI=1S/C22H17N3O2S/c26-28(27,21-11-5-2-6-12-21)15-13-19-17-25(20-9-3-1-4-10-20)24-22(19)18-8-7-14-23-16-18/h1-17H/b15-13+

Clave InChI: XQRTVPNJBHFDFY-FYWRMAATSA-N

SMILES: C1=CC=C(C=C1)N2C=C(C(=N2)C3=CN=CC=C3)/C=C/S(=O)(=O)C4=CC=CC=C4

DDO-6691

CAS: 2640292-52-8

DDO-6691 is an inhibitor of heat shock protein 90 (HSP90). It exhibits antiproliferative effects against various tumor cells, with the highest sensitivity observed in HCT-116 colon cancer cells (IC50: 1.08 μM). DDO-6691 also demonstrates potent tumor growth inhibition in HCT-116 xenograft mouse models.

Fórmula: C₂₂H₁₇N₃O₂S

Forma y color: Solid

Peso molecular: 387.45

Ref: TM-T207588