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CAS 2734919-82-3

:

(E)-Octinoxate-13C,d3

Fórmula:C18H23D3O3
Sinónimos:
  • (E)-Octinoxate-13C,d3
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  • 2-Ethylhexyl(E)-3-(4-(methoxy-D3) phenyl)acrylate

    CAS:
    2-Ethylhexyl(E)-3-(4-(methoxy-D3) phenyl)acrylate is the deuterated form of Octinoxate. Octinoxate (Octyl methoxycinnamate) acts as an agonist of thyroid hormone receptors, leading to a reduction in triiodothyronine (T3) and thyroxine (T4) levels, as well as the transcription levels of type II deiodinase (deio2) related genes in Japanese Medaka. Commonly used as a safe ultraviolet (UV) filter in aquatic environments, Octinoxate inhibits CYP1A1 and CYP1B1, and influences hyaluronic acid (HA) metabolism in human keratinocytes through a PI3K pathway-dependent manner. It also exhibits both anti-estrogenic and anti-androgenic effects in vitro and in vivo.
    Fórmula:C18H26O3
    Peso molecular:293.42

    Ref: TM-T211147

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