CAS 2767440-24-2

Fórmula: C41H52N6O6S2

InChI: InChI=1S/C41H52N6O6S2/c1-26(28-9-11-30(12-10-28)36-27(2)42-25-55-36)43-38(50)34-22-31(48)23-47(34)39(51)37(41(3,4)5)45-35(49)8-6-7-19-53-32-15-13-29(14-16-32)33-24-54-40(44-33)46-17-20-52-21-18-46/h9-16,24-26,31,34,37,48H,6-8,17-23H2,1-5H3,(H,43,50)(H,45,49)/t26-,31+,34-,37+/m0/s1

Clave InChI: GGBZAQUSRYNTSQ-ASCDMGAVSA-N

SMILES: CC1=C(SC=N1)C2=CC=C(C=C2)[C@H](C)NC(=O)[C@@H]3C[C@H](CN3C(=O)[C@H](C(C)(C)C)NC(=O)CCCCOC4=CC=C(C=C4)C5=CSC(=N5)N6CCOCC6)O

(2S,4R)-1-[(2S)-3,3-dimethyl-2-(5-{4-[2-(morpholin-4-yl)-1,3-thiazol-4-yl]phenoxy}pentanamido)butanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]pyrrolidine-2-carboxamide

CAS: 2767440-24-2

(2S,4R)-1-[(2S)-3,3-dimethyl-2-(5-{4-[2-(morpholin-4-yl)-1,3-thiazol-4-yl]phenoxy}pentanamido)butanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]pyrrolidine-2-carboxamide

Fórmula: C₄₁H₅₂N₆O₆S₂

Pureza: 99.34%

Peso molecular: 789.02

Ref: 54-OR1133214

(2S,4R)-1-[(2S)-3,3-dimethyl-2-(5-{4-[2-(morpholin-4-yl)-1,3-thiazol-4-yl]phenoxy}pentanamido)butanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]pyrrolidine-2-carboxamide

CAS: 2767440-24-2

Pureza: 99.34%

Ref: IN-DA029J3F

PROTAC AR-V7 degrader-1

CAS: 2767440-24-2

Potent, oral AR-V7 degrader (Compound 6); DC50: 0.32µM; targets AR-DBD via VHL E3; EC50: 0.88µM in 22Rv1 cells.

Fórmula: C₄₁H₅₂N₆O₆S₂

Forma y color: Solid

Peso molecular: 789.02

Ref: TM-T74410