CAS 27740-01-8
:Escutelarina
Descripción:
Escutelarina es un glucósido flavonoide derivado principalmente de la planta Scutellaria baicalensis, comúnmente conocida como escutelaria de Baikal. Se caracteriza por su estructura química, que incluye un esqueleto de flavona unido a un moiety de glucosa. Escutelarina exhibe diversas actividades biológicas, incluyendo efectos antioxidantes, antiinflamatorios y neuroprotectores, lo que lo hace de interés en la investigación farmacológica. El compuesto es soluble en agua y presenta una estabilidad moderada en condiciones estándar. Sus posibles aplicaciones terapéuticas se están explorando en áreas como enfermedades neurodegenerativas y salud cardiovascular. Además, se ha estudiado Escutelarina por su capacidad para modular diversas vías de señalización, contribuyendo a sus diversos efectos farmacológicos. Al igual que muchos compuestos naturales, la eficacia y seguridad de Escutelarina están sujetas a investigaciones en curso, particularmente en lo que respecta a su biodisponibilidad y mecanismos de acción en sistemas biológicos.
Fórmula:C21H18O12
InChI:InChI=1S/C21H18O12/c22-8-3-1-7(2-4-8)10-5-9(23)13-11(31-10)6-12(14(24)15(13)25)32-21-18(28)16(26)17(27)19(33-21)20(29)30/h1-6,16-19,21-22,24-28H,(H,29,30)/t16-,17-,18+,19-,21+/m0/s1
Clave InChI:InChIKey=DJSISFGPUUYILV-ZFORQUDYSA-N
SMILES:O=C1C=2C(OC(=C1)C3=CC=C(O)C=C3)=CC(O[C@@H]4O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]4O)=C(O)C2O
Sinónimos:- 5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl β-<span class="text-smallcaps">D</span>-glucopyranosiduronic acid
- 7-(beta-D-Glucopyranuronosyloxy)-5,6-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
- Flavone, 4′,5,6,7-tetrahydroxy-, 7-β-<span class="text-smallcaps">D</span>-glucopyranuronoside
- Glucopyranosiduronic acid, 5,6-dihydroxy-2-(p-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl, β-<span class="text-smallcaps">D</span>-
- Scutellarein 7-O-β-<span class="text-smallcaps">D</span>-glucuronide
- Scutellarein 7-O-β-glucuronide
- Scutellarein 7-glucuronide
- Scutellarein 7-β-<span class="text-smallcaps">D</span>-glucuronide
- Scutellarein 7-β-<span class="text-smallcaps">D</span>-glucuronoside
- Scutellarin B
- β-<span class="text-smallcaps">D</span>-Glucopyranosiduronic acid, 5,6-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl
- Glucopyranosiduronic acid, 5,6-dihydroxy-2-(p-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl, β-D-
- Flavone, 4′,5,6,7-tetrahydroxy-, 7-β-D-glucopyranuronoside
- β-D-Glucopyranosiduronic acid, 5,6-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl
- Scutellarin
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(2S,3S,4S,5R,6S)-6-((5,6-Dihydroxy-2-(4-Hydroxyphenyl)-4-Oxo-4H-Chromen-7-Yl)Oxy)-3,4,5-Trihydroxytetrahydro-2H-Pyran-2-Carboxylic Acid
CAS:(2S,3S,4S,5R,6S)-6-((5,6-Dihydroxy-2-(4-Hydroxyphenyl)-4-Oxo-4H-Chromen-7-Yl)Oxy)-3,4,5-Trihydroxytetrahydro-2H-Pyran-2-Carboxylic AcidFórmula:C21H18O12Pureza:98%Peso molecular:462.36Scutellarin
CAS:Fórmula:C21H18O12Pureza:(HPLC) ≥ 98.0%Forma y color:Yellow to brown powderPeso molecular:462.36Scutellarin
CAS:Scutellarin analytical standard provided with w/w absolute assay, to be used for quantitative titration.Fórmula:C21H18O12Pureza:(HPLC) ≥98%Forma y color:PowderPeso molecular:462.37Scutellarin (Standard)
CAS:Scutellarin (Standard) is a reference standard for research and analysis in studies involving Scutellarin. Scutellarin (Scutellarein-7-glucuronide), an active flavone isolated from Scutellaria baicalensis, can inhibit RANKL-mediated MAPK and NF-κB signaling pathway in osteoclasts, and down-regulate the STAT3/Girdin/Akt signaling in HCC cells.Fórmula:C21H18O12Peso molecular:462.3604Scutellarin
CAS:Scutellarin has many pharmacological effects, such as antioxidant, antitumor, antiviral, neuroprotection and antiinflammatory activities. It down-regulates the STAT3/Girdin/Akt signaling in HCC cells, and inhibits RANKL-mediated MAPK and NF-κB signaling pathway in osteoclasts.Fórmula:C21H18O12Pureza:95%~99%Peso molecular:462.363Scutellarin
CAS:Applications Scutellarin is an active flavonoid component from the medical plant Erigeron breviscapus (Vant) Hand-Mazz. Scutellarin is used as a micrpcirculation promoter for the treatment of cardio-cerebrovascular diseases. Studies suggest that Scutellarin has anti-cancer properties and has been shown to enhance apoptosis of tumor cells.
References Gao, C. et al.: Drug Metab. Dispos., 39, 2034 (2011); Chan, J.Y. et al.: Anticancer Res., 29, 3043 (2009); Wang, C.-Z. et al.: Phytomedicine, 17, 63 (2010);Fórmula:C21H18O12Forma y color:NeatPeso molecular:462.36Scutellarin
CAS:(2S,3S,4S,5R,6S)-6-((5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acidFórmula:C21H18O12Pureza:97%Peso molecular:462.36Scutellarin
CAS:Scutellarin from Scutellaria inhibits RANKL in osteoclasts and STAT3/Girdin/Akt in HCC cells.Fórmula:C21H18O12Pureza:98.64% - 99.75%Forma y color:SolidPeso molecular:462.3604Scutellarin
CAS:Natural glycosideFórmula:C21H18O12Pureza:≥ 95.0 % (HPLC)Forma y color:PowderPeso molecular:462.37Scutellarin
CAS:Scutellarin is a bioactive flavonoid compound, which is derived primarily from the plant Scutellaria baicalensis and other species within the Scutellaria genus. As a naturally occurring phytochemical, Scutellarin exerts its effects through multiple biological pathways, including antioxidant, anti-inflammatory, and anti-apoptotic activities.
Fórmula:C21H18O12Pureza:Min. 95%Forma y color:Yellow PowderPeso molecular:462.36 g/mol(2S,3S,4S,5R,6S)-6-{[4,6-dihydroxy-2-(4-hydroxyphenyl)-5-oxo-5H-chromen-7-yl]oxy}-3,4,5-trihydroxyoxane-2-carboxylic acid
CAS:Pureza:98%Peso molecular:462.3630066
