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CAS 2809982-26-9

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  • EGFR-IN-133
    Targetmol
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    EGFR-IN-133

    CAS:
    <p>EGFR-IN-133 (Compound 24) serves as an inhibitor targeting various mutations of the EGFR, including the wild type, L858R/T790M, d19/T790M, L858R/T790M/C797S, and d19/T790M/C797S with respective IC50 values of 0.1, 0.044, 0.036, 0.04, and 0.054 nM. The compound exhibits favorable pharmacokinetic properties and high oral bioavailability.</p>
    Fórmula:C27H29F2N7O3
    Forma y color:Solid
    Peso molecular:537.56

    Ref: TM-T201790