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CAS 2845188-22-7

:

Methanesulfonamide, N-[6-[[5-bromo-2-[[5-ethyl-2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-4-pyrimidinyl]amino]-2,3-dihydro-1,4-benzodioxin-5-yl]-N-methyl-

Fórmula:C33H45BrN8O5S
InChI:InChI=1S/C33H45BrN8O5S/c1-6-22-19-26(29(45-4)20-27(22)42-11-9-23(10-12-42)41-15-13-39(2)14-16-41)37-33-35-21-24(34)32(38-33)36-25-7-8-28-31(47-18-17-46-28)30(25)40(3)48(5,43)44/h7-8,19-21,23H,6,9-18H2,1-5H3,(H2,35,36,37,38)
Clave InChI:CQTOOGAZLNRRLG-UHFFFAOYSA-N
SMILES:CCC1=CC(=C(C=C1N2CCC(CC2)N3CCN(CC3)C)OC)NC4=NC=C(C(=N4)NC5=C(C6=C(C=C5)OCCO6)N(C)S(=O)(=O)C)Br
Sinónimos:
  • Methanesulfonamide, N-[6-[[5-bromo-2-[[5-ethyl-2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-4-pyrimidinyl]amino]-2,3-dihydro-1,4-benzodioxin-5-yl]-N-methyl-
Se han encontrado 1 productos.
  • WZH-15-125
    Targetmol
    + Info

    WZH-15-125

    CAS:
    WZH-15-125 is a potent ALK inhibitor capable of overcoming resistance, particularly with complex ALK mutations. It exhibits an IC50 of 101.7 nM against the highly recalcitrant Lorlatinib-resistant G1202R/L1196M mutation. Additionally, WZH-15-125 can serve as a PROTAC target protein ligand for synthesizing PROTACWZH-17-002. This compound is applicable in non-small cell lung cancer research.
    Fórmula:C33H45BrN8O5S
    Forma y color:Solid
    Peso molecular:745.73

    Ref: TM-T210936

    10mg
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