CAS 2851993-77-4

Fórmula: C26H31N5O4S

InChI: InChI=1S/C26H31N5O4S/c1-35-24-10-6-5-9-23(24)29-15-17-30(18-16-29)26(32)21-11-13-22(14-12-21)36(33,34)31-19-27-25(28-31)20-7-3-2-4-8-20/h5-6,9-14,19-20H,2-4,7-8,15-18H2,1H3

Clave InChI: HMWIALSNZLCBBI-UHFFFAOYSA-N

SMILES: COC1=CC=CC=C1N2CCN(CC2)C(=O)C3=CC=C(C=C3)S(=O)(=O)N4C=NC(=N4)C5CCCCC5

RJG-2051

CAS: 2851993-77-4

RJG-2051 is a selective covalent inhibitor of aldo-keto reductase family 1 member C3 (AKR1C3), with an IC50 value of 13 nM. It interferes with the metabolism of substrates such as androgens, estrogens, and prostaglandins through AKR1C3. RJG-2051 holds potential for cancer research.

Fórmula: C₂₆H₃₁N₅O₄S

Forma y color: Solid

Peso molecular: 509.62

Ref: TM-T206799