CAS 28608-75-5

Orientina

Descripción:

Orientina, con el número CAS 28608-75-5, es un glucósido flavonoide que se encuentra principalmente en varias plantas, particularmente en las hojas de ciertas especies como el trigo sarraceno común y en algunas hierbas. Se caracteriza por su color amarillento y es conocido por sus propiedades antioxidantes, que contribuyen a sus posibles beneficios para la salud. Orientina es soluble en agua y presenta un sabor dulce debido a su estructura glucósidica. Este compuesto se estudia a menudo por sus efectos farmacológicos, incluyendo actividades antiinflamatorias, antidiabéticas y neuroprotectoras. Además, Orientina puede desempeñar un papel en la protección de las células contra el estrés oxidativo y se ha investigado por su potencial en la promoción de la salud cardiovascular. Su presencia en fuentes dietéticas sugiere que puede contribuir a los beneficios generales para la salud asociados con una dieta rica en plantas. Al igual que muchos flavonoides, la biodisponibilidad y eficacia de Orientina pueden verse influenciadas por varios factores, incluyendo el método de extracción y la presencia de otros compuestos en el material de origen.

Fórmula: C₂₁H₂₀O₁₁

InChI: InChI=1S/C21H20O11/c22-6-14-17(28)18(29)19(30)21(32-14)16-11(26)4-10(25)15-12(27)5-13(31-20(15)16)7-1-2-8(23)9(24)3-7/h1-5,14,17-19,21-26,28-30H,6H2/t14-,17-,18+,19-,21+/m1/s1

Clave InChI: InChIKey=PLAPMLGJVGLZOV-VPRICQMDSA-N

SMILES: OC=1C(=C2C(C(=O)C=C(O2)C3=CC(O)=C(O)C=C3)=C(O)C1)[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O

Sinónimos:

• (1S)-1,5-anhydro-1-[2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-8-yl]-D-glucitol
• 2-(3,4-Dihydroxyphenyl)-8-beta-D-glucopyranosyl-5,7-dihydroxy-4H-1-benzopyran-4-one
• 2-(3,4-Dihydroxyphenyl)-8-β-<span class="text-smallcaps">D</span>-glucopyranosyl-5,7-dihydroxy-4H-1-benzopyran-4-one
• 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-8-β-<span class="text-smallcaps">D</span>-glucopyranosyl-5,7-dihydroxy-
• 8-β-<span class="text-smallcaps">D</span>-Glucopyranosyl-3′,4′,5,7-tetrahydroxyflavone
• Luteolin 8-C-glucoside
• Luteolin 8-C-β-<span class="text-smallcaps">D</span>-glucopyranoside
• Luteolin 8-C-β-glucopyranoside
• Luteolin-8-glucoside
• Lutexin
• Orientin (flavone)
• Luteolin 8-C-β-D-glucopyranoside
• 2-(3,4-Dihydroxyphenyl)-8-β-D-glucopyranosyl-5,7-dihydroxy-4H-1-benzopyran-4-one
• Orientin

Orientin

CAS: 28608-75-5

Fórmula: C₂₁H₂₀O₁₁

Pureza: >98.0%(HPLC)

Forma y color: White to Light yellow powder to crystal

Peso molecular: 448.38

Ref: 3B-O0503

2-(3,4-Dihydroxyphenyl)-5,7-Dihydroxy-8-((2S,3R,4R,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-Yl)-4H-Chromen-4-One

CAS: 28608-75-5

2-(3,4-Dihydroxyphenyl)-5,7-Dihydroxy-8-((2S,3R,4R,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-Yl)-4H-Chromen-4-One

Fórmula: C₂₁H₂₀O₁₁

Pureza: 99%

Peso molecular: 448.38

Ref: 54-OR1009712

Orientin

CAS: 28608-75-5

Orientin

Fórmula: C₂₁H₂₀O₁₁

Pureza: 99.5%

Forma y color: Solid

Peso molecular: 448.38

Ref: 54-BUP11077

Orientin

CAS: 28608-75-5

Fórmula: C₂₁H₂₀O₁₁

Peso molecular: 448.38

Ref: 4Z-O-107001

Orientin

CAS: 28608-75-5

Fórmula: C₂₁H₂₀O₁₁

Pureza: ≥ 97.0%

Forma y color: Yellow powder

Peso molecular: 448.38

Ref: 7W-GC4819

Orientin 100 µg/mL in Acetonitrile:Water

Producto controlado

CAS: 28608-75-5

Fórmula: C₂₁H₂₀O₁₁

Forma y color: Single Solution

Peso molecular: 448.38

Ref: 04-A15743000WL-100

Orientin

CAS: 28608-75-5

Fórmula: C₂₁H₂₀O₁₁

Forma y color: Neat

Peso molecular: 448.38

Ref: 04-C15743000

4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-8-β-D-glucopyranosyl-5,7-dihydroxy-

CAS: 28608-75-5

Fórmula: C₂₁H₂₀O₁₁

Pureza: 60%

Forma y color: Solid

Peso molecular: 448.3769

Ref: IN-DA002VV3

Orientin (Standard)

CAS: 28608-75-5

Orientin (Standard) is a reference standard for research and analysis in studies involving Orientin. 1. Orientin (Luteolin-8-glucoside) may be regarded as a candidate therapeutic agent for treatment of vascular inflammatory diseases via inhibition of the HMGB1 signaling pathway. 2. Orientin protects vascular barrier integrity by inhibiting hyperpermeability, expression of CAMs, and adhesion and migration of leukocytes, thereby endorsing its usefulness as a therapy for vascular inflammatory diseases. 3. Orientin has neuroprotection effect by the intracellular mediation of caspase activity; may alleviate cognitive deficits and oxidative stress in AD mice; can exert antidepressant-like effects on CUMS mice, specifically by improving central oxidative stress, neurotransmission, and neuroplasticity.

Fórmula: C₂₁H₂₀O₁₁

Forma y color: Solid

Peso molecular: 448.3769

Ref: TM-TMSM-1796

Orientin

CAS: 28608-75-5

Orientin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Fórmula: C₂₁H₂₀O₁₁

Pureza: (HPLC) ≥99%

Forma y color: Powder

Peso molecular: 448.38

Ref: 11-1054S

Orientin

CAS: 28608-75-5

Orientin has various activities including anti-oxidant, anti-aging, anti-viral, anti-bacterial, anti-inflammation, vasodilatation and cardioprotective, antiadipogenesis, antinociceptive, radiation protective, neuroprotective, and antidepressant-like effects. Orientin protects H9c2 cardio-mytocytes against I/R-induced apoptosis by modulating the mPTP opening, and this role of orientin may involve the PI3K/Akt signaling pathway; it also can decrease C/EBPα and PPARγ protein expression level in 3T3-L1 cells.

Fórmula: C₂₁H₂₀O₁₁

Pureza: 95%~99%

Peso molecular: 448.38

Ref: BP-BP1042

Orientin

Producto controlado

CAS: 28608-75-5

Stability Hygroscopic
Applications Orientin is a flavone, a chemical flavonoid compound. Orientin have been investigated for its anti-oxidant, antihypertensive and antihyperlipidemic effects.
References Yao, H., et al.: Food Chem., 135, 2802 (2012); Gordon, A., et al.: Food Chem., 133, 256 (2012); Cermak, R., et al.: Expert. Opin. Drug. Metab. Toxicol., 4, 17 (2008);

Fórmula: C₂₁H₂₀O₁₁

Forma y color: Neat

Peso molecular: 448.38

Ref: TR-O674900

2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-8-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)-4H-chromen-4-one

CAS: 28608-75-5

2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-8-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)-4H-chromen-4-one

Fórmula: C₂₁H₂₀O₁₁

Pureza: 60% +(HPLC)

Peso molecular: 448.38

Ref: IN-DG01415500

Orientin

CAS: 28608-75-5

1.

Fórmula: C₂₁H₂₀O₁₁

Pureza: 98.77% - 99.96%

Forma y color: Yellow Powder

Peso molecular: 448.3769

Ref: TM-T6S0721

Orientin

CAS: 28608-75-5

Natural glycoside

Fórmula: C₂₁H₂₀O₁₁

Pureza: ≥ 98.0 % (HPLC)

Forma y color: Powder

Peso molecular: 448.38

Ref: 5G-89746

Orientin

CAS: 28608-75-5

Orientin (Luteolin-8-C-glucoside) is a flavonoid that has been shown to have biological properties, such as anti-inflammatory and antioxidant activities, which may be due to its ability to inhibit toll-like receptor 4. Orientin is an effective inhibitor of the growth of Leishmania amazonensis in vitro. It also inhibits the growth of Candida glabrata, a fungus that causes oral thrush and other infections. Orientin has been shown to have high values in inflammatory bowel diseases (IBD).

Fórmula: C₂₁H₂₀O₁₁

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 448.38 g/mol

Ref: 3D-MO08113

Orientin

CAS: 28608-75-5

Fórmula: C₂₁H₂₀O₁₁

Peso molecular: 448.4

Ref: BE-RMT12150

Orientin

CAS: 28608-75-5

Fórmula: C₂₁H₂₀O₁₁

Peso molecular: 448.4

Ref: BE-RMCO060000

ORIENTIN

CAS: 28608-75-5

Pureza: 98.0%

Forma y color: Solid

Peso molecular: 448.3800049

Ref: 10-F859737

Orientin

CAS: 28608-75-5

Fórmula: C₂₁H₂₀O₁₁

Peso molecular: 448.38

Ref: ST-EA-CP-O53000