CAS 2878441-72-4

2-[2-(1-Methylethyl)phenyl]-7-[[4-[1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl]phenyl]methyl]imidazo[5,1-f][1,2,4]triazine

Fórmula: C₂₆H₂₃F₃N₆

InChI: InChI=1S/C26H23F3N6/c1-16(2)20-6-4-5-7-21(20)24-31-14-19-13-30-23(35(19)33-24)12-17-8-10-18(11-9-17)25-32-22(15-34(25)3)26(27,28)29/h4-11,13-16H,12H2,1-3H3

Clave InChI: UHFCLSOFQYEZKD-UHFFFAOYSA-N

SMILES: CC(C)C1=CC=CC=C1C2=NN3C(=CN=C3CC4=CC=C(C=C4)C5=NC(=CN5C)C(F)(F)F)C=N2

Sinónimos:

• USP1-IN-4
• 2-[2-(1-Methylethyl)phenyl]-7-[[4-[1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl]phenyl]methyl]imidazo[5,1-f][1,2,4]triazine

USP1-IN-4

CAS: 2878441-72-4

USP1-IN-4 (compound 10) serves as a potent inhibitor of USP1, exhibiting an IC 50 of 2.44 nM. It demonstrates anticancer properties and operates synergistically with various anticancer drugs [1].

Fórmula: C₂₆H₂₃F₃N₆

Forma y color: Solid

Peso molecular: 476.50

Ref: TM-T87600