CAS 2918263-09-7

LBA-3

Fórmula: C₁₈H₁₈O₅

Sinónimos:

• LBA-3

LBA-3

CAS: 2918263-09-7

LBA-3, a selective and orally active inhibitor of the sodium-coupled citrate transporter SLC13A5, exhibits an IC50 of 67 nM. This compound effectively reduces triglyceride and total cholesterol levels in both oleic and palmitic acid (OPA)-stimulated AML12 cells and PCN-stimulated primary mouse hepatocytes, as well as in mouse models, without showing detectable toxicity. Additionally, LBA-3 is permeable to the blood-brain barrier [1].

Fórmula: C₁₈H₁₈O₅

Forma y color: Solid

Peso molecular: 314.33

Ref: TM-T86803