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CAS 2957895-40-6

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Fórmula:C21H20N6O3
InChI:InChI=1S/C21H20N6O3/c22-18(29)21-26-25-20(30-21)15-11-23-27-17(28)10-16(24-19(15)27)14-8-6-13(7-9-14)12-4-2-1-3-5-12/h6-12,23H,1-5H2,(H2,22,29)
Clave InChI:LYGVANBJVUFZNA-UHFFFAOYSA-N
SMILES:C1CCC(CC1)C2=CC=C(C=C2)C3=CC(=O)N4C(=N3)C(=CN4)C5=NN=C(O5)C(=O)N
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    Targetmol
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    YAP/TEAD-IN-2-1

    CAS:
    YAP/TEAD-IN-2 (Compound T-1) is an inhibitor of YAP/TEAD. This compound suppresses luciferase activity driven by YAP/TEAD in 293T cells and exhibits strong antiproliferative effects on human pleural mesothelioma NCI-H226 cells. YAP/TEAD-IN-2 is applicable for studying diseases associated with disruptions in the Hippo pathway, particularly cancer.
    Fórmula:C21H20N6O3
    Peso molecular:404.43

    Ref: TM-T213630