CAS 301177-43-5

Fórmula: C20H23N3OS

InChI: InChI=1S/C20H23N3OS/c1-13-8-9-14(2)16(10-13)12-25-20-22-18(15-6-4-3-5-7-15)17(11-21)19(24)23-20/h8-10,15H,3-7,12H2,1-2H3,(H,22,23,24)

Clave InChI: LSHOSZQLVLPEGG-UHFFFAOYSA-N

SMILES: CC1=CC(=C(C=C1)C)CSC2=NC(=C(C(=O)N2)C#N)C3CCCCC3

ESI-08

CAS: 301177-43-5

ESI-08

Fórmula: C₂₀H₂₃N₃OS

Pureza: ≥95%

Peso molecular: 353.48

Ref: 54-BUP01612

ESI-08

CAS: 301177-43-5

Fórmula: C₂₀H₂₃N₃OS

Peso molecular: 353.4811

Ref: IN-DA01EQG7

ESI-08

CAS: 301177-43-5

4-Cyclohexyl-2-((2,5-dimethylbenzyl)thio)-6-oxo-1,6-dihydropyrimidine-5-carbonitrile

Fórmula: C₂₀H₂₃N₃OS

Pureza: 99%

Peso molecular: 353.48

Ref: IN-DG01171436

ESI-08

CAS: 301177-43-5

ESI-08 is a drug that has been shown to have potent anti-cancer effects. It is a novel compound that inhibits the protein kinase AKT, which is an important mediator of the metabolic, proliferative, and survival pathways in mammalian cells. ESI-08 also has inhibitory activities on cardiac arrhythmia and cardiac hypertrophy. This drug colocalizes with mitochondria in cardiac cells, suggesting that it may be used as a mitochondrial targeting agent. ESI-08 has also been shown to have potent antagonistic effects against cancer cells, inhibiting their proliferation and inducing apoptosis.

Fórmula: C₂₀H₂₃N₃OS

Pureza: Min. 95%

Peso molecular: 353.5 g/mol

Ref: 3D-BMA17743

ESI-08

CAS: 301177-43-5

ESI-08 is an effective antagonist of EPAC2 with an IC50 of 8.4 μM. ESI-08 selectively blocks cAMP-induced EPAC activation but not cAMP-mediated PKA activation.

Fórmula: C₂₀H₂₃N₃OS

Pureza: 97.17%

Forma y color: White Solid

Peso molecular: 353.481

Ref: TM-T11234