CAS 3034840-18-8

Fórmula: C26H29N3O4

InChI: InChI=1S/C26H29N3O4/c1-30-24-12-17(13-25(31-2)26(24)32-3)21-15-28-16-22-19(21)6-11-33-23-14-18(4-5-20(22)23)29-9-7-27-8-10-29/h4-5,12-16,27H,6-11H2,1-3H3

Clave InChI: QFFKJPJEWNRMHC-UHFFFAOYSA-N

SMILES: COC1=CC(=CC(=C1OC)OC)C2=C3CCOC4=C(C3=CN=C2)C=CC(=C4)N5CCNCC5

M4K2308

CAS: 3034840-18-8

M4K2308, a selective ALK2 ether-linked inhibitor, demonstrates an IC₅₀ of 2 nM and exhibits greater specificity for ALK2 over ALK5, with an IC₅₀ of 224 nM for ALK5. This compound holds potential for research into Diffuse Intrinsic Pontine Glioma (DIPG).

Fórmula: C₂₆H₂₉N₃O₄

Peso molecular: 447.53

Ref: TM-T201837