CAS 3057939-67-7

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Fórmula: C₃₈H₅₇ClN₉O₇P

Sinónimos:

• [Synonyms]

Lys-PEG3-BA

CAS: 3057939-67-7

Lys-PEG3-BA is a PROTAC degrader targeting EML4-ALK/EGFR, with DC50 values of 1.32 μM for H3122 cells (expressing EML4-ALK fusion protein) and 19.66 μM for H1975 cells (with EGFRL858R/T790M mutations). In vitro studies show that Lys-PEG3-BA can inhibit the proliferation of non-small cell lung cancer cells by modulating the ubiquitin-proteasome system. Lys-PEG3-BA is applicable for research related to non-small cell lung cancer.

Fórmula: C₃₈H₅₇ClN₉O₇P

Peso molecular: 818.35

Ref: TM-T217126