CAS 3080315-51-8

Fórmula: C20H19F2N3O

InChI: InChI=1S/C20H19F2N3O/c21-16-7-14(9-24-18(16)22)13-3-6-25(17(26)8-13)20-10-19(11-20,12-20)15-1-4-23-5-2-15/h1-2,4-5,7,9,13H,3,6,8,10-12H2/t13-,19?,20?/m0/s1

Clave InChI: CQWDQYHGKDJKCT-LJLKPOLSSA-N

SMILES: C1CN(C(=O)C[C@H]1C2=CC(=C(N=C2)F)F)C34CC(C3)(C4)C5=CC=NC=C5

SARM1-IN-6

CAS: 3080315-51-8

SARM1-IN-6 (Compound 17a) is a brain-penetrant orthosteric inhibitor of SARM1. It exhibits an IC₅₀ of 14 nM against NAM and 74 nM against HEK cells.

Fórmula: C₂₀H₁₉F₂N₃O

Peso molecular: 355.38

Ref: TM-T210944