CAS 3107307-79-6

Fórmula: C64H73ClN14O10S

InChI: InChI=1S/C64H73ClN14O10S/c1-5-51-61(70-44-18-30-88-31-19-44)73-62(58(72-51)59(66)81)71-45-10-15-53(56(33-45)87-4)77-26-28-78(29-27-77)57(80)38-68-52-14-12-48(35-54(52)79(83)84)90(85,86)74-63(82)49-13-11-46(34-55(49)89-47-32-41-17-21-67-60(41)69-37-47)76-24-22-75(23-25-76)39-42-16-20-64(2,3)36-50(42)40-6-8-43(65)9-7-40/h6-15,17,21,32-35,37,44,68H,5,16,18-20,22-31,36,38-39H2,1-4H3,(H2,66,81)(H,67,69)(H,74,82)(H2,70,71,73)

Clave InChI: XKXKLLHVPVBOFG-UHFFFAOYSA-N

SMILES: CCC1=C(N=C(C(=N1)C(=O)N)NC2=CC(=C(C=C2)N3CCN(CC3)C(=O)CNC4=C(C=C(C=C4)S(=O)(=O)NC(=O)C5=C(C=C(C=C5)N6CCN(CC6)CC7=C(CC(CC7)(C)C)C8=CC=C(C=C8)Cl)OC9=CN=C1C(=C9)C=CN1)[N+](=O)[O-])OC)NC1CCOCC1

CG-3-246

CAS: 3107307-79-6

CG-3-246 is a dual inhibitor targeting FLT3 and BCL-2, with dissociation constants (Kd) of 63 nM and 4.25 nM, respectively. This compound plays a significant role in acute myeloid leukemia research.

Fórmula: C₆₄H₇₃ClN₁₄O₁₀S

Forma y color: Solid

Peso molecular: 1265.87

Ref: TM-T204272