CAS 3108486-39-8

Fórmula: C27H22FN3O4S

InChI: InChI=1S/C27H22FN3O4S/c1-17-14-20(28)8-6-19(17)16-36(34,35)30-21-9-11-22(12-10-21)31-24-13-7-18-4-2-3-5-23(18)27(24)29-25(32)15-26(31)33/h2-14,30H,15-16H2,1H3,(H,29,32)

Clave InChI: YEBHYBSHXPKIRM-UHFFFAOYSA-N

SMILES: CC1=C(C=CC(=C1)F)CS(=O)(=O)NC2=CC=C(C=C2)N3C(=O)CC(=O)NC4=C3C=CC5=CC=CC=C54

P2X4 antagonist-4

CAS: 3108486-39-8

P2X4 antagonist-4 (compound 64) is a potent P2X4R antagonist with an IC50 value of 8 µM. It can inhibit ATP-induced activation of the NLRP3 inflammasome and the subsequent release of IL-1β.

Fórmula: C₂₇H₂₂FN₃O₄S

Forma y color: Solid

Peso molecular: 503.545

Ref: TM-T204441