CAS 3116709-87-3

Fórmula: C72H123N9O6

InChI: InChI=1S/C72H123N9O6/c1-4-7-10-13-16-19-22-25-28-31-34-37-40-43-46-49-52-79-58-67(73-76-79)61-85-70(82)64-55-65(71(83)86-62-68-59-80(77-74-68)53-50-47-44-41-38-35-32-29-26-23-20-17-14-11-8-5-2)57-66(56-64)72(84)87-63-69-60-81(78-75-69)54-51-48-45-42-39-36-33-30-27-24-21-18-15-12-9-6-3/h55-60H,4-54,61-63H2,1-3H3

Clave InChI: CGFCVRAJWNQSDJ-UHFFFAOYSA-N

SMILES: CCCCCCCCCCCCCCCCCCN1C=C(N=N1)COC(=O)C2=CC(=CC(=C2)C(=O)OCC3=CN(N=N3)CCCCCCCCCCCCCCCCCC)C(=O)OCC4=CN(N=N4)CCCCCCCCCCCCCCCCCC

VEGFR-2-IN-64

CAS: 3116709-87-3

VEGFR-2-IN-64 (Compound 28) is an inhibitor of VEGFR2 with an IC₅₀ of 27.8 nM. It suppresses the proliferation of cancer cells A549, T-47D, and Caco-2, exhibits anti-migration and anti-colony formation activities in T-47D cells, and induces apoptosis in T-47D cells.

Fórmula: C₇₂H₁₂₃N₉O₆

Forma y color: Solid

Peso molecular: 1210.8

Ref: TM-T204271