CAS 32449-98-2

(3beta,22alpha,25R)-espirosol-5-en-3-il 4-O-(6-desoxi-alfa-L-manopiranosil)-beta-D-glucopiranósido

Descripción:

La sustancia química conocida como "(3beta,22alpha,25R)-espirosol-5-en-3-il 4-O-(6-desoxi-alfa-L-manopiranosil)-beta-D-glucopiranósido," con el número CAS 32449-98-2, es un glucósido que presenta un esqueleto de spirosolano, que es un tipo de estructura similar a un esteroide. Este compuesto se caracteriza por la presencia de un marco de carbono espiral, que contribuye a su conformación tridimensional única. La molécula contiene un grupo de azúcar, específicamente un grupo 6-deoxi-alfa-L-mannopiranosilo unido a un beta-D-glucopiranósido, lo que indica que tiene tanto complejidad glucosídica como estereoquímica. La presencia de múltiples grupos hidroxilo en los componentes de azúcar mejora su solubilidad en disolventes polares y puede contribuir a su actividad biológica. Tales compuestos a menudo exhiben diversas propiedades farmacológicas, incluidos posibles efectos antiinflamatorios o antimicrobianos, lo que los hace de interés en la química medicinal. La estereoquímica específica en las posiciones 3, 22 y 25 es crucial para sus interacciones biológicas y estabilidad general.

Fórmula: C₃₉H₆₃NO₁₁

InChI: InChI=1/C39H63NO11/c1-18-8-13-39(40-16-18)19(2)28-26(51-39)15-25-23-7-6-21-14-22(9-11-37(21,4)24(23)10-12-38(25,28)5)48-36-33(46)31(44)34(27(17-41)49-36)50-35-32(45)30(43)29(42)20(3)47-35/h6,18-20,22-36,40-46H,7-17H2,1-5H3/t18-,19+,20+,22+,23-,24+,25+,26+,27-,28+,29+,30-,31-,32-,33-,34-,35+,36-,37+,38+,39-/m1/s1

Clave InChI: KRQDMAXNTWLTDZ-HCTICQNOSA-N

SMILES: C[C@@H]1CC[C@@]2([C@H]([C@H]3[C@@H](O2)C[C@@H]4[C@@]3(CC[C@H]5[C@H]4CC=C6[C@@]5(CC[C@@H](C6)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO)O[C@H]8[C@@H]([C@@H]([C@H]([C@@H](O8)C)O)O)O)O)O)C)C)C)NC1

Sinónimos:

• beta-D-glucopyranoside, (3beta,22alpha,25R)-spirosol-5-en-3-yl 4-O-(6-deoxy-alpha-L-mannopyranosyl)-
• (3beta,22alpha,25R)-Spirosol-5-en-3-yl 4-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside
• β-D-Glucopyranoside, (3β,22α,25R)-spirosol-5-en-3-yl 4-O-(6-deoxy-α-L-mannopyranosyl)-
• beta2-Solamargine
• Khasianine 32449-98-2
• o-α-L-rhaMnopyranosyl-(1 → 4 glu)-O-(3)-β-D-glucopyranosyl solasadine
• khasianine
• β2-Solamargine
• b-D-Glucopyranoside, (3b,22a,25R)-spirosol-5-en-3-yl 4-O-(6-deoxy-a-L-mannopyranosyl)-
• KHASIANINE;Β2-SOLAMARGINE

Khasianine

CAS: 32449-98-2

Khasianine

Fórmula: C₃₉H₆₃NO₁₁

Pureza: ≥98%

Peso molecular: 721.92

Ref: 54-BUP09314

Khasianine

CAS: 32449-98-2

Fórmula: C₃₉H₆₃NO₁₁

Peso molecular: 721.93

Ref: 7W-GY3604

Khasianine

CAS: 32449-98-2

Fórmula: C₃₉H₆₃NO₁₁

Pureza: 98%

Forma y color: Solid

Peso molecular: 721.9176

Ref: IN-DA00CIID

Khasianine (Standard)

CAS: 32449-98-2

Khasianine (Standard) is a reference standard for research and analysis in studies involving Khasianine. Khasianine has strong activity against liver damage induced by CCl4.

Fórmula: C₃₉H₆₃NO₁₁

Forma y color: Solid

Peso molecular: 721.9176

Ref: TM-TMSM-2258

Khasianine

CAS: 32449-98-2

Khasianine exhibits strong activity against liver damage induced by CCl4.

Fórmula: C₃₉H₆₃NO₁₁

Pureza: 95%~99%

Peso molecular: 721.929

Ref: BP-BP0830

Khasianine

CAS: 32449-98-2

Khasianine has strong activity against liver damage induced by CCl4.

Fórmula: C₃₉H₆₃NO₁₁

Pureza: 98% - 99.93%

Forma y color: Solid

Peso molecular: 721.9176

Ref: TM-T4035

Khasianine

CAS: 32449-98-2

Natural alkaloid

Fórmula: C₃₉H₆₃NO₁₁

Pureza: ≥ 95.0 % (HPLC)

Peso molecular: 721.92

Ref: 5G-84230

Khasianine

CAS: 32449-98-2

Fórmula: C₃₉H₆₃NO₁₁

Peso molecular: 721.9

Ref: BE-RMT21404

Khasianine

Producto controlado

CAS: 32449-98-2

Stability Hygroscopic
Applications Khasianine is a steroidal glycoalkaloid which is obtained from black nightshade (Solanum Nigrum L.) which displays antitumor activity.
References Ding, X. et al.: Food. Chem., 141, 1181 (2013);

Fórmula: C₂₄H₂₆O₅S

Forma y color: Neat

Peso molecular: 426.525

Ref: TR-K520000

Khasianine

CAS: 32449-98-2

Khasianine is a diterpenoid alkaloid that has potent inhibitory activity against the growth of cancer cells. Khasianine has been shown to induce apoptosis in MCF-7 cells. It inhibits the synthesis of DNA, RNA, and protein by binding to the hydroxyl group on the 3' position of DNA, which prevents transcription and replication. Khasianine also has significant cytotoxicity in a hydroxyl matrix effect study. This drug is extracted from plants using an extractant such as ethyl acetate or dichloromethane. The chemical structure of khasonine is similar to that of steroidal alkaloids, with a glycosidic bond between two molecules. The molecular weight is 313 Da and it can be identified by its nmr spectra

Fórmula: C₃₉H₆₃NO₁₁

Pureza: Min. 95%

Peso molecular: 721.92 g/mol

Ref: 3D-HBA44998