CAS 332-80-9

1-Metil-L-histidina

Descripción:

1-Metil-L-histidina, con el número CAS 332-80-9, es un derivado de aminoácido que ocurre de forma natural a partir de la histidina. Se caracteriza por la presencia de un grupo metilo unido al átomo de nitrógeno de la cadena lateral imidazólica de la histidina. Esta modificación puede influir en sus propiedades bioquímicas e interacciones. Se sabe que 1-Metil-L-histidina juega un papel en el metabolismo muscular y a menudo se estudia en el contexto de la síntesis de proteínas y la función muscular. Es soluble en agua y exhibe características polares debido a sus grupos funcionales amino y carboxilo. El compuesto se encuentra típicamente en varios sistemas biológicos y puede estar involucrado en vías metabólicas. Su presencia en el tejido muscular se ha relacionado con la regulación de la renovación de proteínas musculares. Como compuesto de investigación, también puede servir como un biomarcador para ciertas condiciones fisiológicas. En general, 1-Metil-L-histidina es significativo tanto en la investigación bioquímica como en aplicaciones clínicas potenciales relacionadas con la salud muscular y el metabolismo.

Fórmula: C₇H₁₁N₃O₂

InChI: InChI=1S/C7H11N3O2/c1-10-3-5(9-4-10)2-6(8)7(11)12/h3-4,6H,2,8H2,1H3,(H,11,12)/t6-/m0/s1

Clave InChI: InChIKey=BRMWTNUJHUMWMS-LURJTMIESA-N

SMILES: C([C@@H](C(O)=O)N)C=1N=CN(C)C1

Sinónimos:

• (2S)-2-Amino-3-(1-methyl-1H-imidazol-4-yl)propanoic acid
• (S)-2-Amino-3-(1-methyl-1H-imidazol-4-yl)propanoic acid
• 1-Methyl-<span class="text-smallcaps">L</span>-histidine
• 1-Methylhistidine
• 1-N-Methyl-<span class="text-smallcaps">L</span>-histidine
• 1-methyl-L-histidine
• <span class="text-smallcaps">L</span>-Histidine, 1-methyl-
• Histidine, 1-methyl-, <span class="text-smallcaps">L</span>-
• N₁-Methyl-<span class="text-smallcaps">L</span>-histidine
• NSC 524367
• π-N-Methyl-<span class="text-smallcaps">L</span>-histidine
• τ-Methylhistidine
• L-Histidine, 1-methyl-
• 1-N-Methyl-L-histidine

H-His(1-Me)-OH

CAS: 332-80-9

(S)-2-Amino-3-(1-methyl-1H-imidazol-4-yl)propanoic acid

Fórmula: C₇H₁₁N₃O₂

Pureza: 97%

Peso molecular: 169.18

Ref: IN-DG10065

1-Methyl-L-histidine

CAS: 332-80-9

Fórmula: C₇H₁₁N₃O₂

Pureza: 98%

Forma y color: Solid

Peso molecular: 169.1811

Ref: IN-DA0032T9

1-Methyl-L-histidine

CAS: 332-80-9

Peso molecular: 169.18

Ref: 7W-GM5450

1-Methyl-L-histidine

CAS: 332-80-9

1-Methyl-L-histidine

Fórmula: C₇H₁₁N₃O₂

Pureza: ≥98%

Peso molecular: 169.18

Ref: 54-BUP06200

H-His(1-Me)-OH H-His(t-Me)-OH

CAS: 332-80-9

H-His(1-Me)-OH H-His(t-Me)-OH

Fórmula: C₇H₁₁N₃O₂

Pureza: 98%

Forma y color: Solid

Peso molecular: 169.18114

Ref: 54-OR36342

1-Methyl-L-histidine

Producto controlado

CAS: 332-80-9

Applications The urinary 1- and 3-methylhistidine (1- and 3-MH) metabolites as potential biomarkers of skeletal muscle toxicity. These metabolites were highly correlated to sex-, dose-, and time-dependent development of cerivastatin-induced myotoxicity. Natural but non-proteinogenic amino acid; employed as index of muscle protein breakdown.
References Berna, M., et al.: Anal. Chem., 79, 4199 (2007), Pritt, M., et al.: Toxicol. Sci., 103, 382 (2008), Tonomura, Y., et al.: Toxicology, 266, 48 (2009),

Fórmula: C₇H₁₁N₃O₂

Forma y color: Neat

Peso molecular: 169.18

Ref: TR-M312050

1-Methyl-L-histidine

CAS: 332-80-9

1-Methyl-L-histidine is an amino acid that is a component of protein. It is a potential biomarker for detecting inflammation and may be used as an indicator of renal function. 1-Methyl-L-histidine has been shown to be higher in the serum of diabetic patients than in healthy individuals, although it is not yet known if this difference is due to the disease or other factors. The chemical structure of 1-methyl-L-histidine consists of one methyl group attached to histidine. 1-Methyl-L-histidine fluoresces at a wavelength of 364 nm when excited with ultraviolet light at 315 nm. The fluorescence emission spectrum can be used as a measure for kinetic data on protein synthesis in vivo, such as the rate at which tryptophan is incorporated into proteins.

Fórmula: C₇H₁₁N₃O₂

Pureza: Min. 98 Area-%

Forma y color: Powder

Peso molecular: 169.18 g/mol

Ref: 3D-FM25864

1-Methyl-L-histidine

CAS: 332-80-9

1-Methyl-L-histidine (3-(1-Methylimidazol-4-yl)-L-alanine) is a natural but non-proteinogenic amino acid; employed as index of muscle protein breakdown.

Fórmula: C₇H₁₁N₃O₂

Pureza: 99.79% - 99.83%

Forma y color: Solid

Peso molecular: 169.18

Ref: TM-T4934

H-His(1-Me)-OH

CAS: 332-80-9

M02991 - H-His(1-Me)-OH

Fórmula: C₇H₁₁N₃O₂

Pureza: 98%

Forma y color: Solid, Yellowish Powder

Peso molecular: 169.184

Ref: 10-M02991

H-His(1-Me)-OH

CAS: 332-80-9

Bachem ID: 4041045.

Fórmula: C₇H₁₁N₃O₂

Pureza: > 99%

Forma y color: White Powder

Peso molecular: 169.18

Ref: 01-4041045