CAS 33419-42-0
:Etopósido
Descripción:
Etopósido es un agente quimioterapéutico utilizado principalmente en el tratamiento de varios tipos de cáncer, incluyendo el cáncer testicular y el cáncer de pulmón de células pequeñas. Se clasifica como un inhibidor de la topoisomerasa II, lo que significa que interfiere con la enzima responsable de la replicación y reparación del ADN, lo que finalmente conduce a la muerte de las células cancerosas. Etopósido se administra típicamente por vía intravenosa u oral y es conocido por su efectividad en combinación con otros fármacos de quimioterapia. El compuesto tiene una fórmula molecular de C21H22O8 y un peso molecular de aproximadamente 366.39 g/mol. Etopósido se caracteriza por su capacidad para inducir apoptosis en las células cancerosas, lo que lo convierte en una herramienta valiosa en oncología. Sin embargo, también puede causar efectos secundarios, incluyendo mielosupresión, trastornos gastrointestinales y un mayor riesgo de malignidades secundarias. Debido a su mecanismo de acción, el monitoreo y la gestión cuidadosa de la dosis son esenciales para minimizar la toxicidad mientras se maximiza la eficacia terapéutica. En general, Etopósido sigue siendo un agente importante en el arsenal contra ciertas malignidades.
Fórmula:C29H32O13
InChI:InChI=1S/C29H32O13/c1-11-36-9-20-27(40-11)24(31)25(32)29(41-20)42-26-14-7-17-16(38-10-39-17)6-13(14)21(22-15(26)8-37-28(22)33)12-4-18(34-2)23(30)19(5-12)35-3/h4-7,11,15,20-22,24-27,29-32H,8-10H2,1-3H3/t11-,15+,20-,21-,22+,24-,25-,26-,27-,29+/m1/s1
Clave InChI:InChIKey=VJJPUSNTGOMMGY-MRVIYFEKSA-N
SMILES:O=C1[C@@]2([C@@H](C=3C([C@@H](O[C@@H]4O[C@]5([C@]([C@H](O)[C@H]4O)(O[C@H](C)OC5)[H])[H])[C@]2(CO1)[H])=CC6=C(C3)OCO6)C7=CC(OC)=C(O)C(OC)=C7)[H]
Sinónimos:- (5R,5aR,8aR,9S)-9-[[4,6-O-(1R)-Ethylidene-β-<span class="text-smallcaps">D</span>-glucopyranosyl]oxy]-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)furo[3′,4′:6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one
- (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl 4,6-O-[(1R)-ethylidene]-alpha-L-gulopyranoside
- (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl 4,6-O-[(1R)-ethylidene]-beta-D-mannopyranoside
- (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl 4,6-O-[(1S)-ethylidene]-alpha-L-gulopyranoside
- (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl 4,6-O-[(1S)-ethylidene]-beta-D-mannopyranoside
- (8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside
- 4'-Demethyl-1-O-[4,6-O-(ethylidene)-β-D-glucopyranosyl]epipodophyllotoxin
- 4'-Demethylepipodophyllotoxin 9-(4,6-O-ethylidene-β-D-glucopyranoside)
- 4'-Demethylepipodophyllotoxin ethylidene-β-D-glucoside
- 4'-Demethylepipodophyllotoxin-(4,6-O-(R)-Ethylidene-Beta-D-Glucopyranoside)
- 4-Demethylepipodophyllotoxin-Beta-D-Ethylideneglucoside
- 4′-Demethyl-1-O-[4,6-O-(ethylidene)-β-<span class="text-smallcaps">D</span>-glucopyranosyl]epipodophyllotoxin
- 4′-Demethylepipodophyllotoxin 9-(4,6-O-ethylidene-β-<span class="text-smallcaps">D</span>-glucopyranoside)
- 4′-Demethylepipodophyllotoxin ethylidene-β-<span class="text-smallcaps">D</span>-glucoside
- Beposid
- Bioposide
- Celltop
- EPE
- Epipodophyllotoxin VP 16213
- Epipodophyllotoxin, 4'-demethyl-, 4,6-O-ethylidene-β-D-glucopyranoside
- Epipodophyllotoxin, 4′-demethyl-, 4,6-O-ethylidene-β-<span class="text-smallcaps">D</span>-glucopyranoside
- Eposed
- Eposin
- Ethopul
- Eto-Gry
- Etoposid
- Etoposido
- Etosid
- Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 9-[(4,6-O-ethylidene-β-D-glucopyranosyl)oxy]-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-, [5R-[5α,5aβ,8aα,9β(R*)]]-
- Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 9-[[4,6-O-(1R)-ethylidene-β-D-glucopyranosyl]oxy]-5,8,8a,9-tetrahy dro-5-(4-hydroxy-3,5-dimethoxyphenyl)-, (5R,5aR,8aR,9S)-
- Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 9-[[4,6-O-(1R)-ethylidene-β-D-glucopyranosyl]oxy]-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-, (5R,5aR,8aR,9S)-
- Furo[3′,4′:6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 9-[(4,6-O-ethylidene-β-<span class="text-smallcaps">D</span>-glucopyranosyl)oxy]-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-, [5R-[5α,5aβ,8aα,9β(R*)]]-
- Furo[3′,4′:6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 9-[[4,6-O-(1R)-ethylidene-β-<span class="text-smallcaps">D</span>-glucopyranosyl]oxy]-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-, (5R,5aR,8aR,9S)-
- Fytop
- Fytosid
- Lastet
- Nsc 141540
- Nzytop
- Pyrano[3,2-d]-1,3-dioxin, furo[3′,4′:6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one deriv.
- Sintopozid
- Topok
- Toposar
- Toposide
- VP 16 (pharmaceutical)
- VePesid
- Vepesid J
- Vp 16
- Vp 16-123
- Vp 16-213
- Zuyeyidal
- trans-Etoposide
- Furo[3′,4′:6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 9-[(4,6-O-ethylidene-β-D-glucopyranosyl)oxy]-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-, [5R-[5α,5aβ,8aα,9β(R*)]]-
- (5R,5aR,8aR,9S)-9-[[4,6-O-(1R)-Ethylidene-β-D-glucopyranosyl]oxy]-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)furo[3′,4′:6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one
- Ver más sinónimos
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Etoposide
CAS:Fórmula:C29H32O13Pureza:>98.0%(HPLC)Forma y color:White to Almost white powder to crystalPeso molecular:588.56Etoposide
CAS:Topoisomerase inhibitor and inducer of apoptosisFórmula:C29H32O13Forma y color:Powder or crystals or crystalline powderPeso molecular:588.56ETOPOSIDE CRS
CAS:ETOPOSIDE CRSFórmula:C29H32O13Forma y color:Crystalline Powder. White. Powder.Peso molecular:588.5566ETOPOSIDE FOR SYSTEM SUITABILITY CRS
CAS:ETOPOSIDE FOR SYSTEM SUITABILITY CRSFórmula:C29H32O13Peso molecular:588.5566Etoposide Resolution Mixture
CAS:Other glycosides, natural or reproduced by synthesis, and their salts, ethers, esters and other derivativesForma y color:White PowderEtoposide
CAS:Other glycosides, natural or reproduced by synthesis, and their salts, ethers, esters and other derivativesFórmula:C29H32O13Forma y color:White Off-White PowderPeso molecular:588.18429Etoposide
CAS:Etoposide (VP-16-213) is a topoisomerase II inhibitor that inhibits DNA synthesis by forming a complex with topoisomerase II and DNA (IC50=60.3 μM).
Fórmula:C29H32O13Pureza:99.19% - 99.94%Forma y color:Crystals From Methanol SolidPeso molecular:588.56(5R,5aR,8aR,9S)-9-[[4,6-O-(1R)-Ethylidene-β-D-glucopyranosyl]oxy]-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one
CAS:Fórmula:C29H32O13Pureza:98%Forma y color:SolidPeso molecular:588.5566Etoposide
CAS:Fórmula:C29H32O13Pureza:(HPLC) ≥ 98.0%Forma y color:White or almost white crystalline powderPeso molecular:588.56Etoposide, USP grade
CAS:Fórmula:C29H32O13Pureza:(anhydrous basis) 95.0 - 105.0 %Forma y color:White or almost white crystalline powderPeso molecular:588.56Etoposide
CAS:Etoposide is a chemotherapy medication used for the treatments of a number of types of cancer. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA, it induces apoptosis in MCF-7 breast cancer cells.Fórmula:C29H32O13Pureza:95%~99%Peso molecular:588.562Etoposide
CAS:EtoposideFórmula:C29H32O13Pureza:99%Forma y color: pale yellow solidPeso molecular:588.56g/mol
![(5R,5aR,8aR,9S)-9-[[4,6-O-(1R)-Ethylidene-β-D-glucopyranosyl]oxy]-5,8,8a,9-tetrahydro-5-(4-hydroxy…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA003A2V.jpg&w=3840&q=75)
