CAS 3416-05-5

3'-desoxitimidina

Descripción:

3'-desoxitimidina, también conocido como dThd o timidina sin el grupo 3'-hidroxilo, es un nucleósido que juega un papel crucial en la estructura del ADN. Consiste en una base de timina unida a un azúcar desoxirribosa. La ausencia del grupo hidroxilo en la posición 3' lo distingue de la timidina regular, lo que tiene implicaciones para su actividad biológica y utilidad en diversas aplicaciones. Este compuesto es típicamente un polvo cristalino blanco a blanco sucio y es soluble en agua y alcohol. 3'-desoxitimidina es significativo en biología molecular y bioquímica, particularmente en estudios que involucran la síntesis y reparación del ADN, así como en terapias antivirales, donde puede actuar como un sustrato para las ADN polimerasas. Su número CAS, 3416-05-5, es un identificador único que facilita su identificación en bases de datos químicas. En general, 3'-desoxitimidina es un compuesto importante tanto en contextos de investigación como terapéuticos, contribuyendo a nuestra comprensión de la química de los ácidos nucleicos y los procesos celulares.

Fórmula: C₁₀H₁₄N₂O₄

InChI: InChI=1/C10H14N2O4/c1-6-4-12(10(15)11-9(6)14)8-3-2-7(5-13)16-8/h4,7-8,13H,2-3,5H2,1H3,(H,11,14,15)/t7-,8+/m0/s1

Clave InChI: XKKCQTLDIPIRQD-JGVFFNPUSA-N

SMILES: CC1=CN(C(=O)NC1=O)[C@H]2CC[C@H](O2)CO

Sinónimos:

• 2',3'-Dideoxythymidine
• Dideoxythymidine
• Nsc 617596
• Thymidine, 3'-deoxy-
• 1-[(2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methylpyrimidine-2,4(1H,3H)-dione

3'-Deoxythymidine

CAS: 3416-05-5

Fórmula: C₁₀H₁₄N₂O₄

Pureza: >98.0%(HPLC)(T)

Forma y color: White to Light yellow powder to crystal

Peso molecular: 226.23

Ref: 3B-D6100

3'-Deoxythymidine

CAS: 3416-05-5

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Fórmula: C₁₀H₁₄N₂O₄

Peso molecular: 226.23

Ref: 02-J65765

2',3'-Dideoxythymidine

CAS: 3416-05-5

2',3'-Dideoxythymidine

Fórmula: C₁₀H₁₄N₂O₄

Pureza: 97%

Forma y color: Solid-Powder

Peso molecular: 226.22916

Ref: 54-BID2038

2'',3''-Dideoxythymidine

CAS: 3416-05-5

Fórmula: C₁₀H₁₄N₂O₄

Peso molecular: 226.23

Ref: 7W-GN6842

1-((2R,5S)-5-(Hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione

CAS: 3416-05-5

Fórmula: C₁₀H₁₄N₂O₄

Pureza: 98%

Forma y color: Solid

Peso molecular: 226.2292

Ref: IN-DA00I6R2

3'-Deoxythymidine

CAS: 3416-05-5

3'-Deoxythymidine (3DT) is a nucleoside analog that has high resistance to HIV. It is an analogue of the human insulin-like growth factor-1 (IGF-1), which binds to the IGF-1 receptor and inhibits the binding of IGF-1 to its receptor, thereby inhibiting the growth of cells. 3DT has been shown to have a protective effect against radiation in mice, with an LD50 at a dose of 5.0 mg/kg for radiation exposure. 3DT also has antiviral activity against murine sarcoma virus, as well as other biological properties such as enzyme activities and disease activity. This drug may be used in future research on polymerase chain reactions (PCRs) and DNA sequencing, since it is chemically stable and can be easily synthesized.

Fórmula: C₁₀H₁₄N₂O₄

Pureza: Min. 95%

Forma y color: White Powder

Peso molecular: 226.23 g/mol

Ref: 3D-ND06301

1-((2R,5S)-5-(Hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione

CAS: 3416-05-5

Fórmula: C₁₀H₁₄N₂O₄

Pureza: 98%

Peso molecular: 226.232

Ref: 10-F211267

1-((2R,5S)-5-(Hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione

CAS: 3416-05-5

1-((2R,5S)-5-(Hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione

Fórmula: C₁₀H₁₄N₂O₄

Pureza: 97%

Peso molecular: 226.23

Ref: IN-DG86458

2,3-Dideoxythymidine (3-Deoxythymidine, ddT) extrapure, 98%

CAS: 3416-05-5

Fórmula: C₁₀H₁₄N₂O₄

Pureza: min. 98 %

Forma y color: White to pale yellow, Powder

Peso molecular: 226.23

Ref: SR-22328

3′-Deoxy Thymidine

CAS: 3416-05-5

3′-Deoxy Thymidine is a nucleoside analog of thymidine with antiviral activity. 3′-Deoxy Thymidine inhibit HIV replication in peripheral blood mononuclear cells (EC₅₀ = 0.17 µM). 3′-Deoxy Thymidine also decreases plaque formation in CV-1 cells infected with HSV-1 at micromolar concentrations. These properties support the use of 3′-Deoxy Thymidine in antiviral mechanism studies and nucleoside analog evaluation.

Fórmula: C₁₀H₁₄N₂O₄

Pureza: 99.89%

Forma y color: White Solid

Peso molecular: 226.23

Ref: TM-T84987