CAS 356068-97-8

Fórmula: C20H23FN4O2

InChI: InChI=1S/C20H23FN4O2/c1-4-22-7-8-23-20(27)18-11(2)17(24-12(18)3)10-15-14-9-13(21)5-6-16(14)25-19(15)26/h5-6,9-10,22,24H,4,7-8H2,1-3H3,(H,23,27)(H,25,26)/b15-10-

Clave InChI: LIZNIAKSBJKPQC-GDNBJRDFSA-N

SMILES: CCNCCNC(=O)C1=C(NC(=C1C)/C=C\2/C3=C(C=CC(=C3)F)NC2=O)C

Desethyl Sunitinib ((Z)-N-(2-(ethylamino)ethyl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide)

CAS: 356068-97-8

Lactams, nesoi

Fórmula: C₂₀H₂₃FN₄O₂

Forma y color: Orange Solid

Peso molecular: 370.1805

Ref: 45-1A05060

(Z)-N-(2-(Ethylamino)ethyl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide

CAS: 356068-97-8

Fórmula: C₂₀H₂₃FN₄O₂

Pureza: 95%

Forma y color: Solid

Peso molecular: 370.4206

Ref: IN-DA007A8Y

(Z)-N-(2-(Ethylamino)ethyl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide

CAS: 356068-97-8

(Z)-N-(2-(Ethylamino)ethyl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide

Fórmula: C₂₀H₂₃FN₄O₂

Pureza: 95%+

Peso molecular: 370.42

Ref: 54-PC1032748

N-Desethyl Sunitinib

CAS: 356068-97-8

Fórmula: C₂₀H₂₃FN₄O₂

Forma y color: Orange Solid

Peso molecular: 370.43

Ref: 4Z-S-412

N-Desethylsunitinib

CAS: 356068-97-8

Forma y color: Neat

Ref: 61-FOR3568.06

N-Desethylsunitinib

Producto controlado

CAS: 356068-97-8

Fórmula: C₂₀H₂₃FN₄O₂

Forma y color: Neat

Peso molecular: 370.42

Ref: 86-MM3568.06

N-Desethyl Sunitinib

CAS: 356068-97-8

N-Desethyl Sunitinib (SU012662) is inhibitor of tyrosine kinases tumor proliferation and angiogenesis, including VEGFR, PDGFR, KIT, and FLT3,

Fórmula: C₂₀H₂₃FN₄O₂

Pureza: 98%

Forma y color: Solid

Peso molecular: 370.42

Ref: TM-T12145

N-Desethyl sunitinib

CAS: 356068-97-8

N-Desethyl sunitinib is an active metabolite of sunitinib. It has been shown to have antitumor response in experimental models, suggesting that it may be a potential biomarker for renal cell cancer. Sunitinib is used in the treatment of cancers such as renal cell cancer and gastrointestinal stromal tumor. N-Desethyl sunitinib has also been shown to affect drug metabolism through the induction of CYP3A4 and CYP2D6, which can lead to drug interactions. This metabolite is detected in human serum by high performance liquid chromatography with a matrix effect analyzer, but not by LC-MS/MS.

Fórmula: C₂₀H₂₃FN₄O₂

Pureza: Min. 95 Area-%

Forma y color: Powder

Peso molecular: 370.42 g/mol

Ref: 3D-FD21182

N-Desethyl Sunitinib

CAS: 356068-97-8

Ref: BE-RMCS226012

N-Desethyl Sunitinib-d4 Maleate

Producto controlado

CAS: 356068-97-8

Applications N-Desethyl Sunitinib-d4 Maleate, is the labeled analogue of N-Desethyl Sunitinib (D289650), a metabolite of Sunitinib (S820000).
References Sun, L., et al.: J. Med. Chem., 46, 1116 (2003), Mendel, D.B., et al.: Clin. Cancer Res., 9, 327 (2003), Sistla, A., et al.: Drug Dev. Ind. Pharm., 30, 19 (2004), Sakamoto, K.M., et al.: Curr. Opin. Invest. Drugs, 5. 1329 (2004),

Fórmula: C₂₀H₁₉D₄FN₄O₂•C₄H₄O₄

Forma y color: Neat

Peso molecular: 347.4511607

Ref: TR-D289653

N-Desethyl Sunitinib

CAS: 356068-97-8

Fórmula: C₂₀H₂₃FN₄O₂

Peso molecular: 370.43

Ref: ST-EA-CP-S42022