CAS 3599-32-4

Verde de indocianina

Descripción:

Verde de indocianina (ICG) es un colorante sintético utilizado principalmente en diagnósticos médicos, particularmente en oftalmología e imágenes cardiovasculares. Se caracteriza por su color verde oscuro y su fuerte absorción en la región del infrarrojo cercano del espectro electromagnético, lo que lo hace especialmente útil para la imagen fluorescente. La estructura química de ICG incluye un esqueleto de colorante cianina, que contribuye a sus propiedades ópticas únicas. ICG es soluble en agua y tiene un perfil de toxicidad relativamente bajo, lo que mejora su idoneidad para aplicaciones clínicas. Tras la administración, se une a proteínas plasmáticas, lo que permite una visualización efectiva del flujo sanguíneo y la perfusión tisular. Su rápida eliminación del torrente sanguíneo, principalmente a través del hígado, es otra característica notable. Además, ICG se utiliza en diversas aplicaciones más allá de la imagen, incluyendo la evaluación de la función hepática y la guía de procedimientos quirúrgicos. En general, sus propiedades distintivas hacen de Verde de indocianina una herramienta valiosa tanto en entornos diagnósticos como terapéuticos.

Fórmula: C₄₃H₄₇N₂NaO₆S₂

InChI: InChI=1/C43H48N2O6S2.Na/c1-42(2)36-26-24-32-18-10-12-20-34(32)40(36)44(28-14-16-30-52(46,47)48)38(42)22-8-6-5-7-9-23-39-43(3,4)37-27-25-33-19-11-13-21-35(33)41(37)45(39)29-15-17-31-53(49,50)51;/h5-13,18-27H,14-17,28-31H2,1-4H3,(H-,46,47,48,49,50,51);/q;+1/p-1/rC43H47N2NaO6S2/c1-42(2)36-26-24-32-18-10-12-20-34(32)40(36)44(28-14-16-30-53(47,48)49)38(42)22-8-6-5-7-9-23-39-43(3,4)37-27-25-33-19-11-13-21-35(33)41(37)45(39)29-15-17-31-54(50,51)52-46/h5-13,18-27H,14-17,28-31H2,1-4H3

Clave InChI: InChIKey=AANGVCDSLQANGQ-UHFFFAOYSA-N

SMILES: CC1(C)C2=C([N+](CCCCS(=O)(=O)[O-])=C1C=CC=CC=CC=C3N(CCCCS(=O)(=O)O)C4=C(C3(C)C)C=5C(C=C4)=CC=CC5)C=CC=6C2=CC=CC6.[Na]

Sinónimos:

• 1H-Benz[e]indolium, 2-[7-[1,1-dimethyl-3-(4-sulfobutyl)benz[e]indolin-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-, hydroxide, inner salt, sodium salt
• 1H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e]indol-2-ylidene]-1,3,5-heptatrien-1-yl]-1,1-dimethyl-3-(4-sulfobutyl)-, inner salt, sodium salt (1:1)
• 1H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e]indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-, hydroxide, inner salt, sodium salt
• 1H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e]indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-, inner salt, sodium salt
• 2-{7-[1,3-Dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e]indol-2-ylidene]hepta-1,3,5-trienyl}-1,1-dimethyl-3-(4-sulfobutyl)-1H-benz[e]indolium, hydroxyde, sel interne, sel de sodium
• 4,5-Benzoindotricarbocyanine
• 4-[(2Z)-2-[(2Z,4E,6Z)-7-[3,3-dimethyl-1-(4-sulfonatobutyl)benzo[g]indol-1-ium-2-yl]hepta-2,4,6-trienylidene]-3,3-dimethyl-benzo[g]indol-1-yl]butylsulfonyloxysodium
• Cardio Green
• HWD Indocyanine Green
• ICG
• Indocyanin green
• Ir-125
• Natrium-2-[7-[3,3-dimethyl-1-(4-sulfonatobutyl)benz[e]indolin-2-yliden]hepta-1,3,5-trien-1-yl]-3,3-dimethyl-1-(4-sulfonatobutyl)benz[e]indolinium
• Nk 2611
• Nk 2612
• Opthagreen
• Sacarosa, Bruta (De Cana)
• Saccharose, Brut (De Canne)
• So 270
• Sodium 2-(7-(3,3-Dimethyl-1-(4-Sulfonatobutyl)Benz(E)Indolin-2-Ylidene)Hepta-1,3,5-Trien-Y-1-Yl)-3,3-Dimethyl-1-(4-Sulfonatobutyl)Benz[E]Indolinium
• Sodium 2-(7-(3,3-dimethyl-1-(4-sulfonatobutyl)benz(e)indolin-2-ylidene)hepta-1,3,5-trien-1-yl)-3,3-dimethyl-1-(4-sulfonatobutyl)benz[e]indolinium
• Ujoviridin
• Wofaverdin
• sodium 4-(2-{7-[1,1-dimethyl-3-(4-sulfonatobutyl)-1H-benzo[e]indolium-2-yl]hepta-2,4,6-trien-1-ylidene}-1,1-dimethyl-1,2-dihydro-3H-benzo[e]indol-3-yl)butane-1-sulfonate
• 4-(2-[7-[1,1-DIMETHYL-3-(4-SULFO-BUTYL)-1H-BENZO[E]INDOL-2-YL]-HEPTA-2,4,6-TRIENYLIDENE]-1,1-DIMETHYL-BENZO[E]INDOLIUM-3-YL)-BUTANE-1-SULFONIC ACID SODIUM SALT
• )-1,3,5-heptatrienyl)-1,1-dimethyl-3-(4-sulfobutyl)-,hydroxide,innersalt,
• CARDIOGREEN
• BIS-[1-(4-SULFOBUTYL)-3,3-DIMETHYL-4,5-BENZOINDOLINYLIDEN-2]-HEPTAMETHINECYANINE-BETAINE-SODIUM SALT (INDOCYANINEGREEN, CARDIOGREEN)
• FOXGREEN
• IC GREEN
• INDOCYANINE GREEN
• ,innersalt,sodiumsalt(9ci)

Indocyanine Green

CAS: 3599-32-4

Synthetic organic coloring matter,nesoi

Fórmula: C₄₃H₄₇N₂NaO₆S₂

Forma y color: Green Brown Blue Powder

Peso molecular: 774.27732

Ref: 45-1340009

1H-Benz[e]indolium,2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e]indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-, inner salt, sodiumsalt

CAS: 3599-32-4

Fórmula: C₄₃H₄₇N₂NaO₆S₂

Pureza: 95%

Forma y color: Solid

Peso molecular: 774.9629

Ref: IN-DA00I74W

Indocyanine green

CAS: 3599-32-4

Indocyanine green

Pureza: ≥98%

Peso molecular: 774.96g/mol

Ref: 54-BUP17455

Cardio-Green

CAS: 3599-32-4

Cardio-Green

Pureza: 97%

Peso molecular: 774.96g/mol

Ref: 54-OR1012625

Indocyanine Green

CAS: 3599-32-4

Fórmula: C₄₃H₄₇N₂O₆S₂·Na

Peso molecular: 751.98 22.99

Ref: 4Z-I-134001

Cardiogreen, 95%, USP grade

CAS: 3599-32-4

Fórmula: C₄₃H₄₇N₂NaO₆S₂

Pureza: 90.0 - 105.0 % (dried basis)

Forma y color: Dark green to brown crystalline powder

Peso molecular: 774.96

Ref: 7W-GT1101

Indocyanine green

CAS: 3599-32-4

Indocyanine green (Cardiogreen) is a low toxicic fluorescent agent, is a tricarbocyanine dye,has been widely used in medical diagnostics.

Fórmula: C₄₃H₄₇N₂NaO₆S₂

Pureza: ≥98%

Forma y color: Green To Green With A Brown Cast Powder

Peso molecular: 774.96

Ref: TM-T14875

Indocyanine Green-d12

CAS: 3599-32-4

Fórmula: C₄₃H₃₅D₁₂N₂O₆S₂·Na

Peso molecular: 764.05 22.99

Ref: 4Z-I-134002

Cardiogreen

CAS: 3599-32-4

Fórmula: C₄₃H₄₇N₂NaO₆S₂

Pureza: ≥ 90.0%

Forma y color: Dark green powder

Peso molecular: 774.96

Ref: 7W-GT1409

Indocianine Green RS

CAS: 3599-32-4, 7681-82-5

Forma y color: Dark Greenish Blue Solid Powder

Ref: 2K-2001000021

Indocyanine Green (~90%)

Producto controlado

CAS: 3599-32-4

Fórmula: C₄₃H₄₇N₂O₆S₂·Na

Pureza: ~90%

Forma y color: Neat

Peso molecular: 774.96

Ref: TR-I697000

Indocyanine green

CAS: 3599-32-4

Indocyanine green is a fluorescent dye with a variety of applications in medical imaging. It has been used to diagnose and evaluate the activity of cancer cells and brain functions. Indocyanine green has also been used as an angiographic agent for diagnosis of solid tumours. In addition, it can be used to evaluate liver function and the blood flow in the brain. The biological properties of indocyanine green have not yet been fully elucidated, but it is known that it binds to hepatocyte-like cells in culture and is found at high levels in human serum. This dye shows fluorescence when bound to DNA or RNA, which indicates its possible use as a molecular probe for detecting carcinoma cells. 
Indocyanine green is a STT3B inhibitor and has been shown to prevent α-amanitin toxicity in mice (Wang et al, 2023). This means it could be a possible antidote to poisoning by Amanita, such as death cap mushroom Amanita phalloides, which is the cause of over 90% of fatal mushroom poisoning.

Fórmula: C₄₃H₄₇N₂O₆S₂·Na

Pureza: (%) Min. 95%

Forma y color: Green Powder

Peso molecular: 774.96 g/mol

Ref: 3D-FI10558

Indocyanine Green >d6

Producto controlado

CAS: 3599-32-4

Applications It is the labeled analogue of Indocyanine Green (I697000), a tricarbocyanine type of dye with infrared absorbing properties that can be used as a diagnostic aid (blood volume determination, cardiac output, hepatic function).
References Papageorgiou, P., et al.: Br. J. Dermatol., 142, 973 (2000), Dreno, B., et al.: Dermatology, 203, 135 (2001), Gollnick, H., et al.: Drugs, 63, 1579 (2003), Seaton, E., et al.: Lancet, 362, 1347 (2003),

Fórmula: C₇H₁₄N₂O

Forma y color: Neat

Peso molecular: NA

Ref: TR-I697003

Indocyanine Green

CAS: 3599-32-4

Fórmula: C₄₃H₄₇N₂NaO₆S₂

Forma y color: Light yellow to Amber to Dark green powder to crystal

Peso molecular: 774.97

Ref: 3B-I0535

Indocyanine green

CAS: 3599-32-4

Pureza: 95%

Peso molecular: 774.97

Ref: 10-F868901