CAS 3599-32-4
:Verde de indocianina
Descripción:
Verde de indocianina (ICG) es un colorante sintético utilizado principalmente en diagnósticos médicos, particularmente en oftalmología e imágenes cardiovasculares. Se caracteriza por su color verde oscuro y su fuerte absorción en la región del infrarrojo cercano del espectro electromagnético, lo que lo hace especialmente útil para la imagen fluorescente. La estructura química de ICG incluye un esqueleto de colorante cianina, que contribuye a sus propiedades ópticas únicas. ICG es soluble en agua y tiene un perfil de toxicidad relativamente bajo, lo que mejora su idoneidad para aplicaciones clínicas. Tras la administración, se une a proteínas plasmáticas, lo que permite una visualización efectiva del flujo sanguíneo y la perfusión tisular. Su rápida eliminación del torrente sanguíneo, principalmente a través del hígado, es otra característica notable. Además, ICG se utiliza en diversas aplicaciones más allá de la imagen, incluyendo la evaluación de la función hepática y la guía de procedimientos quirúrgicos. En general, sus propiedades distintivas hacen de Verde de indocianina una herramienta valiosa tanto en entornos diagnósticos como terapéuticos.
Fórmula:C43H47N2NaO6S2
InChI:InChI=1/C43H48N2O6S2.Na/c1-42(2)36-26-24-32-18-10-12-20-34(32)40(36)44(28-14-16-30-52(46,47)48)38(42)22-8-6-5-7-9-23-39-43(3,4)37-27-25-33-19-11-13-21-35(33)41(37)45(39)29-15-17-31-53(49,50)51;/h5-13,18-27H,14-17,28-31H2,1-4H3,(H-,46,47,48,49,50,51);/q;+1/p-1/rC43H47N2NaO6S2/c1-42(2)36-26-24-32-18-10-12-20-34(32)40(36)44(28-14-16-30-53(47,48)49)38(42)22-8-6-5-7-9-23-39-43(3,4)37-27-25-33-19-11-13-21-35(33)41(37)45(39)29-15-17-31-54(50,51)52-46/h5-13,18-27H,14-17,28-31H2,1-4H3
Clave InChI:InChIKey=AANGVCDSLQANGQ-UHFFFAOYSA-N
SMILES:CC1(C)C2=C([N+](CCCCS(=O)(=O)[O-])=C1C=CC=CC=CC=C3N(CCCCS(=O)(=O)O)C4=C(C3(C)C)C=5C(C=C4)=CC=CC5)C=CC=6C2=CC=CC6.[Na]
Sinónimos:- 1H-Benz[e]indolium, 2-[7-[1,1-dimethyl-3-(4-sulfobutyl)benz[e]indolin-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-, hydroxide, inner salt, sodium salt
- 1H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e]indol-2-ylidene]-1,3,5-heptatrien-1-yl]-1,1-dimethyl-3-(4-sulfobutyl)-, inner salt, sodium salt (1:1)
- 1H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e]indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-, hydroxide, inner salt, sodium salt
- 1H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e]indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-, inner salt, sodium salt
- 2-{7-[1,3-Dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e]indol-2-ylidene]hepta-1,3,5-trienyl}-1,1-dimethyl-3-(4-sulfobutyl)-1H-benz[e]indolium, hydroxyde, sel interne, sel de sodium
- 4,5-Benzoindotricarbocyanine
- 4-[(2Z)-2-[(2Z,4E,6Z)-7-[3,3-dimethyl-1-(4-sulfonatobutyl)benzo[g]indol-1-ium-2-yl]hepta-2,4,6-trienylidene]-3,3-dimethyl-benzo[g]indol-1-yl]butylsulfonyloxysodium
- Cardio Green
- HWD Indocyanine Green
- ICG
- Indocyanin green
- Ir-125
- Natrium-2-[7-[3,3-dimethyl-1-(4-sulfonatobutyl)benz[e]indolin-2-yliden]hepta-1,3,5-trien-1-yl]-3,3-dimethyl-1-(4-sulfonatobutyl)benz[e]indolinium
- Nk 2611
- Nk 2612
- Opthagreen
- Sacarosa, Bruta (De Cana)
- Saccharose, Brut (De Canne)
- So 270
- Sodium 2-(7-(3,3-Dimethyl-1-(4-Sulfonatobutyl)Benz(E)Indolin-2-Ylidene)Hepta-1,3,5-Trien-Y-1-Yl)-3,3-Dimethyl-1-(4-Sulfonatobutyl)Benz[E]Indolinium
- Sodium 2-(7-(3,3-dimethyl-1-(4-sulfonatobutyl)benz(e)indolin-2-ylidene)hepta-1,3,5-trien-1-yl)-3,3-dimethyl-1-(4-sulfonatobutyl)benz[e]indolinium
- Ujoviridin
- Wofaverdin
- sodium 4-(2-{7-[1,1-dimethyl-3-(4-sulfonatobutyl)-1H-benzo[e]indolium-2-yl]hepta-2,4,6-trien-1-ylidene}-1,1-dimethyl-1,2-dihydro-3H-benzo[e]indol-3-yl)butane-1-sulfonate
- 4-(2-[7-[1,1-DIMETHYL-3-(4-SULFO-BUTYL)-1H-BENZO[E]INDOL-2-YL]-HEPTA-2,4,6-TRIENYLIDENE]-1,1-DIMETHYL-BENZO[E]INDOLIUM-3-YL)-BUTANE-1-SULFONIC ACID SODIUM SALT
- )-1,3,5-heptatrienyl)-1,1-dimethyl-3-(4-sulfobutyl)-,hydroxide,innersalt,
- CARDIOGREEN
- BIS-[1-(4-SULFOBUTYL)-3,3-DIMETHYL-4,5-BENZOINDOLINYLIDEN-2]-HEPTAMETHINECYANINE-BETAINE-SODIUM SALT (INDOCYANINEGREEN, CARDIOGREEN)
- FOXGREEN
- IC GREEN
- INDOCYANINE GREEN
- ,innersalt,sodiumsalt(9ci)
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Indocyanine Green
CAS:Fórmula:C43H47N2NaO6S2Forma y color:Light yellow to Amber to Dark green powder to crystalPeso molecular:774.97Indocyanine Green
CAS:Synthetic organic coloring matter,nesoiFórmula:C43H47N2NaO6S2Forma y color:Green Brown Blue PowderPeso molecular:774.27732Cardio-Green
CAS:Cardio-GreenFórmula:C43H47N2NaO6S2Pureza:>97%Forma y color:SolidPeso molecular:774.96Cardiogreen
CAS:Fórmula:C43H47N2NaO6S2Pureza:≥ 90.0%Forma y color:Dark green powderPeso molecular:774.96Indocyanine green
CAS:Indocyanine greenFórmula:C43H47N2NaO6S2Pureza:98.5%Forma y color:SolidPeso molecular:774.96Cardiogreen, 95%, USP grade
CAS:Fórmula:C43H47N2NaO6S2Pureza:90.0 - 105.0 % (dried basis)Forma y color:Dark green to brown crystalline powderPeso molecular:774.961H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e]indol-2-ylidene]-1,3,5-heptatrien-1-yl]-1,1-dimethyl-3-(4-sulfobutyl)-, inner salt, sodium salt (1:1)
CAS:Fórmula:C43H47N2NaO6S2Pureza:95%Forma y color:SolidPeso molecular:774.9629Indocyanine Green (~90%)
CAS:Producto controladoFórmula:C43H47N2O6S2·NaPureza:~90%Forma y color:NeatPeso molecular:774.96Indocyanine Green >d6
CAS:Producto controladoApplications It is the labeled analogue of Indocyanine Green (I697000), a tricarbocyanine type of dye with infrared absorbing properties that can be used as a diagnostic aid (blood volume determination, cardiac output, hepatic function).
References Papageorgiou, P., et al.: Br. J. Dermatol., 142, 973 (2000), Dreno, B., et al.: Dermatology, 203, 135 (2001), Gollnick, H., et al.: Drugs, 63, 1579 (2003), Seaton, E., et al.: Lancet, 362, 1347 (2003),Fórmula:C7H14N2OForma y color:NeatPeso molecular:NAIndocyanine green
CAS:Indocyanine green (Cardiogreen) is a low toxicic fluorescent agent, is a tricarbocyanine dye,has been widely used in medical diagnostics.Fórmula:C43H47N2NaO6S2Pureza:98.77%Forma y color:Brown SolidPeso molecular:774.963Indocyanine Green
CAS:Sodium 4-(2-(7-(1,1-dimethyl-3-(4-sulfonatobutyl)-1H-benzo[e]indol-2(3H)-ylidene)hepta-1,3,5-trien-1-yl)-1,1-dimethyl-1H-benzo[e]indol-3-ium-3-yl)butane-1-sulfonateFórmula:C43H47N2NaO6S2Pureza:95%Peso molecular:774.96Indocyanine green
CAS:Indocyanine green is a fluorescent dye with a variety of applications in medical imaging. It has been used to diagnose and evaluate the activity of cancer cells and brain functions. Indocyanine green has also been used as an angiographic agent for diagnosis of solid tumours. In addition, it can be used to evaluate liver function and the blood flow in the brain. The biological properties of indocyanine green have not yet been fully elucidated, but it is known that it binds to hepatocyte-like cells in culture and is found at high levels in human serum. This dye shows fluorescence when bound to DNA or RNA, which indicates its possible use as a molecular probe for detecting carcinoma cells.
Indocyanine green is a STT3B inhibitor and has been shown to prevent α-amanitin toxicity in mice (Wang et al, 2023). This means it could be a possible antidote to poisoning by Amanita, such as death cap mushroom Amanita phalloides, which is the cause of over 90% of fatal mushroom poisoning.Fórmula:C43H47N2O6S2·NaPureza:(%) Min. 95%Forma y color:Green PowderPeso molecular:774.96 g/mol
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