CAS 361465-74-9

AS1604498

CAS: 361465-74-9

AS1604498 is a highly specific, competitive inhibitor of human NAMPT, with an IC50 of 44.4 nM. It functionally suppresses NAMPT enzyme activity, reducing the production of nicotinamide mononucleotide and decreasing intracellular NAD levels, which activates caspase 3/7 and induces apoptosis in cancer cells. AS1604498 can be utilized in research related to chronic myeloid leukemia.

Fórmula: C₁₉H₁₇N₃O₂

Peso molecular: 319.36

Ref: TM-T219135