CAS 366789-02-8
:Rivaroxabán
Descripción:
Rivaroxabán es un medicamento anticoagulante oral que se utiliza principalmente para la prevención y el tratamiento de trastornos tromboembólicos, como la trombosis venosa profunda y la embolia pulmonar. Funciona como un inhibidor directo del factor Xa, lo que interrumpe la cascada de coagulación y reduce la formación de coágulos sanguíneos. Rivaroxabán se caracteriza por su alta biodisponibilidad y farmacocinética predecible, lo que permite una dosificación fija sin necesidad de monitoreo rutinario de los parámetros de coagulación. La sustancia se administra típicamente en forma de tabletas y se absorbe rápidamente, con concentraciones plasmáticas máximas que ocurren dentro de unas pocas horas después de la ingestión. Se metaboliza principalmente en el hígado a través de las enzimas del citocromo P450 y se excreta a través de vías renales y fecales. Los efectos secundarios comunes pueden incluir complicaciones hemorrágicas, lo que requiere precaución en pacientes con ciertos factores de riesgo. El perfil de eficacia y seguridad de Rivaroxabán lo ha convertido en una opción ampliamente utilizada en la terapia anticoagulante, aunque está contraindicado en pacientes con hemorragia activa o deterioro renal severo.
Fórmula:C19H18ClN3O5S
InChI:InChI=1/C19H18ClN3O5S/c20-16-6-5-15(29-16)18(25)21-9-14-10-23(19(26)28-14)13-3-1-12(2-4-13)22-7-8-27-11-17(22)24/h1-6,14H,7-11H2,(H,21,25)/t14-/m0/s1
Clave InChI:InChIKey=KGFYHTZWPPHNLQ-AWEZNQCLSA-N
SMILES:O=C1N(C[C@H](CNC(=O)C=2SC(Cl)=CC2)O1)C3=CC=C(C=C3)N4C(=O)COCC4
Sinónimos:- (S)-Rivaroxaban
- 2-Thiophenecarboxamide, 5-chloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-
- 5-Chloro-N-(((5S)-2-oxo-3-(4-(3-oxomorpholin-4-yl)phenyl)-1,3-oxazolidin-5-yl)methyl)thiophene-2-carboxamide
- 5-Chloro-N-([(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl]-methyl)-2-thiophenecarboxamide
- 5-Chloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-2-thiophenecarboxamide
- 5-Chloro-N-[[(S)-3-(4-(3-oxomorpholin-4-yl)phenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl]-thiophene-2-carboxamide
- 5-chloro-N-[[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]oxazolidin-5-yl]methyl]thiophene-2-carboxamide
- Bay 59-7939
- Rivaroxaban intermediates
- Rivaroxban
- Xarelto
- Rivaroxaban
- (S)-5-chloro-N-((2-oxo-3-(4-(3-oxomorpholino)phenyl)oxazolidin-5-yl)methyl)thiophene-2-carboxamide
- Rivaroxaban API
- Rivarobaxan
- Rivaroxaban(Xarelto)
- (S)-5-Chloro-N-((2-oxo-3-(4-(3-oxomorpholino)phenyl)-oxazolidin-5-yl)methyl)thiophene-2-carboxami
- Rivaroxaba
- Ver más sinónimos
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Encontrado 14 productos.
Rivaroxaban
CAS:Fórmula:C19H18ClN3O5SPureza:>98.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:435.88Rivaroxaban
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFórmula:C19H18ClN3O5SForma y color:White PowderPeso molecular:435.06557Rivaroxaban
CAS:Rivaroxaban (BAY 59-7939) is an oral, direct factor Xa inhibitor with anticoagulant properties, interfering with thrombin formation.Fórmula:C19H18ClN3O5SPureza:99.93% - >99.99%Forma y color:SolidPeso molecular:435.885-chloro-N-{[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl]methyl}thiophene-2-carboxamide
CAS:Fórmula:C19H18ClN3O5SPureza:99%Forma y color:SolidPeso molecular:435.8813Rivaroxaban
CAS:Fórmula:C19H18ClN3O5SPureza:≥ 98.0% (dried basis)Forma y color:White to off-white powderPeso molecular:435.88Rivaroxaban
CAS:<p>Applications A novel antithrombotic agent. A highly potent and selective, direct FXa inhibitor.<br>References Ansell, J., et al.: Drugs, 64, 1 (2004), Eriksson, B., et al.: J. Thromb. Haemost., 3, 103 (2005), Kubitza, D., et al.: Clin. Pharmacol. Ther., 78, 412 (2005),<br></p>Fórmula:C19H18ClN3O5SForma y color:White To BeigePeso molecular:435.88Rivaroxaban - Bio-X ™
CAS:<p>Rivaroxaban is a natural drug that is a direct factor Xa inhibitor. It has been shown to be an effective therapy for the treatment of atrial fibrillation, deep vein thrombosis (DVT) and pulmonary embolism (PE). It works by inhibiting the enzyme, thrombin, which is responsible for the formation of blood clots. Rivaroxaban also has an effect on the coagulation system by decreasing the levels of fibrinogen and increases in antithrombin III. This drug does not have any specific antidote, but it can be reversed with heparin. Pharmacodynamics and drug interactions have been studied extensively in preclinical models, demonstrated by the concentration–time curves.</p>Fórmula:C19H18ClN3O5SPureza:Min. 95%Forma y color:White PowderPeso molecular:435.88 g/molRivaroxaban
CAS:<p>Rivaroxaban is a natural drug that is a direct factor Xa inhibitor. It has been shown to be an effective therapy for the treatment of atrial fibrillation, deep vein thrombosis (DVT) and pulmonary embolism (PE). It works by inhibiting the enzyme, thrombin, which is responsible for the formation of blood clots. Rivaroxaban also has an effect on the coagulation system by decreasing the levels of fibrinogen and increases in antithrombin III. This drug does not have any specific antidote, but it can be reversed with heparin. Pharmacodynamics and drug interactions have been studied extensively in preclinical models, demonstrated by the concentration–time curves.</p>Fórmula:C19H18ClN3O5SPureza:Min. 98 Area-%Forma y color:White Off-White PowderPeso molecular:435.88 g/mol
![5-chloro-N-{[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl]methyl}thiophene-2-c…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA0035KL.jpg&w=3840&q=75)
