CAS 367273-07-2

Fórmula: C22H22ClF2NO4

InChI: InChI=1S/C22H22ClF2NO4/c1-21(2)5-6-22(3,4)16-12(21)9-11(18(27)17(16)23)19(28)26-10-7-13(24)15(20(29)30)14(25)8-10/h7-9,27H,5-6H2,1-4H3,(H,26,28)(H,29,30)

Clave InChI: PNAWUIKCVQSLFG-UHFFFAOYSA-N

SMILES: CC1(CCC(C2=C1C=C(C(=C2Cl)O)C(=O)NC3=CC(=C(C(=C3)F)C(=O)O)F)(C)C)C

AGN 195183

CAS: 367273-07-2

AGN 195183

Fórmula: C₂₂H₂₂ClF₂NO₄

Pureza: 99.76%

Peso molecular: 437.86

Ref: 54-PC1032569

AGN 195183

CAS: 367273-07-2

Fórmula: C₂₂H₂₂ClF₂NO₄

Pureza: 99.76%

Peso molecular: 437.8642

Ref: IN-DA00C6KT

AGN 195183

CAS: 367273-07-2

AGN 195183 is a cell factor that is a specific agonist for the stem cell factor receptor. It can be used to study transcriptional regulation, such as in the case of hepatitis. AGN 195183 has been shown to be a potent inducer of growth and differentiation in primary cells, as well as being an effective inhibitor of cell proliferation when used at high concentrations. AGN 195183 is also a synthetic retinoid that has been shown to stimulate gene expression by binding to nuclear receptors that regulate transcription-polymerase chain reactions (PCR). This compound can also be used to induce differentiation of cultured cells, such as those derived from Mcf-7 cells.

Fórmula: C₂₂H₂₂ClF₂NO₄

Pureza: Min. 95%

Peso molecular: 437.86 g/mol

Ref: 3D-SPA27307

AGN-195183

CAS: 367273-07-2

AGN 195183: RARα agonist, Kd=3 nM, selective, no RARβ/γ effect, inhibits breast cancer cells, in Phase I/II clinical trials, non-irritant.

Fórmula: C₂₂H₂₂ClF₂NO₄

Forma y color: Solid

Peso molecular: 437.864

Ref: TM-T14144